Up&Up Glucosamine HCL + Chondroitin Sulfate Sodium supplement bottle
Up&Up

Glucosamine HCL + Chondroitin Sulfate Sodium Review

What We Researched
3 active ingredients analyzed · 12 inactive ingredients decoded · 3 brand certifications checked · Last updated: Aug 2026
92
Product Score Excellent
76
Brand Score Fair

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Chondroitin Sulfate Sodium 1200 mg
Glucosamine Hydrochloride 1500 mg
Bioavailability Very Good

Absorption Rating

  • Chondroitin Sulfate Sodium Good
  • Glucosamine Hydrochloride Fair
Other Ingredients Excellent

Fillers & Additives

  • Carnauba Wax
  • Croscarmellose Sodium
  • Crospovidone
  • Gum Arabic
  • Hydroxypropyl Methylcellulose
  • Magnesium Stearate
  • Microcrystalline Cellulose
  • Natural Vanilla Flavor
  • Polyethylene Glycol Low
  • Propylene Glycol
  • Silica
  • Stearic Acid
Efficacy Excellent

Dosage Analysis

  • Chondroitin Sulfate Sodium 1200 mg Effective
  • Glucosamine Hydrochloride 1500 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
Sodium 110 mg
Chondroitin Sulfate Sodium 1200 mg
Glucosamine Hydrochloride 1500 mg

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Carnauba Wax Safe

Provides a glossy, protective coating on tablets.

Croscarmellose Sodium Safe

Helps tablets break apart and dissolve quickly in the stomach.

Crospovidone Generally_safe

It is used as a binder to help tablets or capsules disintegrate.

Gum Arabic Safe

It is used as a thickener, binder, or emulsifier.

Hydroxypropyl Methylcellulose Safe

It is used as a coating for tablets and capsules.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Natural Vanilla Flavor Generally_safe

It is used to enhance the taste of the supplement.

Polyethylene Glycol Caution

It is used as a binder, coating agent, or to improve solubility.

Propylene Glycol Generally_safe

It is used as a solvent to dissolve ingredients.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Brand Trust Report
Up&Up

Founded 2009 · Minneapolis, Minnesota, United States · 295 products · target.com/b/up-up/-/N-5v60y

Certifications

3 certifications
Nsf Gmp Verified Source
NSF Contents Certified Verified
Gluten-Free Certified Verified

Transparency

3 claims
Third Party Testing Claim — Claimed
In House Testing — Claimed

Violation History

6 incidents
Lawsuit Failure to disclose the presence of heavy metals in prenatal vitamins.2022Source
Lawsuit Failure to disclose the presence of heavy metals in prenatal vitamins.2022Source
Recall Up and Up Childrens Acetaminophen2021-10-26Source
Lawsuit Deceptively marketing biotin supplements with unsubstantiated health claims.2017Source
Lawsuit Falsely marketing the health benefits of biotin supplements.2017Source
Recall Up&Up Multipurpose Solution2010-12-22Source
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Frequently Asked Questions
Is Up&Up Glucosamine HCL + Chondroitin Sulfate Sodium a good supplement?

Up&Up Glucosamine HCL + Chondroitin Sulfate Sodium received a product quality score of 92/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 3 active ingredients with 90 servings per container. Of the 12 inactive ingredients, 8 are rated safe and 1 are flagged for review. The manufacturer, Up&Up, holds a brand trust score of 76/100 with 3 verified certifications including Nsf Gmp, NSF Contents Certified, Gluten-Free Certified.

What are the ingredients in Up&Up Glucosamine HCL + Chondroitin Sulfate Sodium?

Up&Up Glucosamine HCL + Chondroitin Sulfate Sodium contains 3 active ingredients: Sodium (110 mg), Chondroitin Sulfate Sodium (1200 mg), Glucosamine Hydrochloride (1500 mg). Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Up&Up Glucosamine HCL + Chondroitin Sulfate Sodium safe to take?

Up&Up Glucosamine HCL + Chondroitin Sulfate Sodium has been analyzed for ingredient safety across all its components. Of 12 inactive ingredients, 8 are rated safe. 1 ingredient is flagged for review: Polyethylene Glycol. 'Caution' doesn't mean dangerous — it indicates the ingredient has some considerations worth being aware of, such as potential sensitivities or ongoing research. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Up&Up a trustworthy supplement brand?

Up&Up receives a brand trust score of 76/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 2009 and headquartered in Minneapolis, Minnesota, United States, the company offers 295 products in their lineup. They hold 3 verified certifications including Nsf Gmp, NSF Contents Certified, Gluten-Free Certified. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Up&Up has 6 historical regulatory incidents on record, which are factored into the trust score.

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This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 150,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

How to use turmeric?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 150,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

How to take turmeric for inflammation?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 150,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.