Crospovidone

Generally Safe BinderSynthetic

Crospovidone is a synthetic binder used in dietary supplements. Safety rating: Generally Safe. It is generally considered safe for most people at standard doses. Found in 20 supplements in the GoodSupp database. Crospovidone is a synthetic polymer used as a binder and disintegrant.

20 Products use this
Generally Safe Safety rating
Binder Category
No Natural origin

Safety Verdict: Generally Safe

This ingredient is rated generally safe for use in dietary supplements.

What is Crospovidone?

Crospovidone is a synthetic polymer used as a binder and disintegrant.

Common Names Crospovidone, Crosslinked PVP
Type Binder
Origin Synthetic / Manufactured
Safety Rating Generally Safe

Why is Crospovidone used in supplements?

It is used as a binder to help tablets or capsules disintegrate.

Role in supplements: Binder — holds tablet ingredients together so they don't crumble.

Should you be concerned about Crospovidone?

Generally no. Crospovidone is considered safe for most people at typical supplement doses. Some individuals may want to be aware of minor sensitivities.

Low risk. Generally safe for most people in supplement amounts.

Top-rated products containing Crospovidone

These 20 highest-scoring supplements in our database use Crospovidone.

Nature's Bounty Anxiety & Stress Relief
Nature's Bounty Anxiety & Stress Relief
Product 100 Brand N/A
Nature's Bounty Anxiety & Stress Relief
Nature's Bounty Anxiety & Stress Relief
Product 100 Brand N/A
Nature's Bounty Biotin Strawberry 5,000 mcg Quick Dissolve Tablets
Nature's Bounty Biotin Strawberry 5,000 mcg Quick Dissolve Tablets
Product 100 Brand N/A
Blackmores Glucosamine Sulfate One-A-Day, Vanilla, 1,500 mg
Blackmores Glucosamine Sulfate One-A-Day, Vanilla, 1,500 mg
Product 100 Brand N/A
tnvitamins B12 1000 mcg Sublingual
tnvitamins B12 1000 mcg Sublingual
Product 100 Brand N/A
Puritan's Pride Doctor's Trust Red Yeast Rice 1200 mg
Puritan's Pride Doctor's Trust Red Yeast Rice 1200 mg
Product 100 Brand N/A
Nature's Truth Fast Dissolve B-12 1,000 mg Natural Berry Flavor
Nature's Truth Fast Dissolve B-12 1,000 mg Natural Berry Flavor
Product 100 Brand N/A
Puritan's Pride Ashwagandha KSM-66 & L-Theanine
Puritan's Pride Ashwagandha KSM-66 & L-Theanine
Product 100 Brand N/A
Nature's Truth Fast Dissolve Ultra Biotin 5,000 mcg Natural Berry Flavor
Nature's Truth Fast Dissolve Ultra Biotin 5,000 mcg Natural Berry Flavor
Product 100 Brand N/A
Natrol Biotin 1,000 mcg Strawberry
Natrol Biotin 1,000 mcg Strawberry
Product 100 Brand N/A
Puritan's Pride Calcium Citrate
Puritan's Pride Calcium Citrate
Product 100 Brand N/A
Natrol CoQ-10 100 mg Fast Dissolve Cherry Flavor
Natrol CoQ-10 100 mg Fast Dissolve Cherry Flavor
Product 100 Brand N/A
Puritan's Pride Calcium Citrate
Puritan's Pride Calcium Citrate
Product 100 Brand N/A
Natrol Biotin 5,000 mcg Strawberry
Natrol Biotin 5,000 mcg Strawberry
Product 100 Brand N/A
Natrol Vitamin D3 1,000 IU Fast Dissolve Natural Strawberry Flavor
Natrol Vitamin D3 1,000 IU Fast Dissolve Natural Strawberry Flavor
Product 100 Brand N/A
Jamieson Vitamin B12 Fast-Dissolving Tablets 1000 mcg
Jamieson Vitamin B12 Fast-Dissolving Tablets 1000 mcg
Product 100 Brand N/A
Jamieson Jamieson Vitamin B12 (Methylcobalamin)1,000 mcg Fast Dissolving Sublingual Tablets, 100 sublingual tablets
Jamieson Jamieson Vitamin B12 (Methylcobalamin)1,000 mcg Fast Dissolving Sublingual Tablets, 100 sublingual tablets
Product 100 Brand N/A
Jamieson Vitamin B12 Methylcobalamin Fast-Dissolving Tablets 1000 mcg
Jamieson Vitamin B12 Methylcobalamin Fast-Dissolving Tablets 1000 mcg
Product 100 Brand N/A
Jamieson Vitamin D3 1,000 IU Fast Dissolving Sublingual Tablets
Jamieson Vitamin D3 1,000 IU Fast Dissolving Sublingual Tablets
Product 100 Brand N/A
Jamieson Vitamin B12 Tablets 2500 mcg Fast-Dissolving Cherry Flavour
Jamieson Vitamin B12 Tablets 2500 mcg Fast-Dissolving Cherry Flavour
Product 100 Brand N/A
Related Ingredients
Acacia Generally Safe Acacia Gum Safe Croscarmellose Generally Safe Croscarmellose Sodium Safe Gum Acacia^ Generally Safe Hydrogenated Polyisobutene Generally Safe Hydroxypropyl Cellulose Safe Hydroxypropylcellulose Generally Safe
Frequently Asked Questions
Is Crospovidone safe in supplements?

Crospovidone is rated generally safe for most people at amounts commonly found in supplements. While the overall safety profile is favorable, some individuals may experience minor sensitivities. In GoodSupp's database, 20 products contain this ingredient. Consult your healthcare provider if you have specific concerns.

What is Crospovidone and why is it in my supplement?

Crospovidone is a synthetic polymer used as a binder and disintegrant. As a binder, it holds tablet ingredients together so they maintain their shape and don't crumble during handling. It appears in 20 products in the GoodSupp database.

Is Crospovidone natural or synthetic?

Crospovidone is synthetically produced, meaning it is manufactured through chemical processes rather than directly extracted from natural sources. Synthetic ingredients are extremely common in supplements and are not inherently less safe than natural alternatives. In many cases, synthetic production allows for higher purity and more consistent quality. The FDA regulates both natural and synthetic supplement ingredients under the same safety standards. GoodSupp rates ingredients based on their actual safety data regardless of whether they're natural or synthetic.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.