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NatureWise 5-HTP Plus+, 60 Vegetarian Capsules supplement bottle
NatureWise

5-HTP Plus+, 60 Vegetarian Capsules Review

What We Researched
2 active ingredients analyzed · 5 inactive ingredients decoded · 7 brand certifications checked · Page generated: Sep 2026
93
Product Score Excellent
90
Brand Score Excellent

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg 290%
5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) 200 mg †
Bioavailability Very Good

Absorption Rating

  • Vitamin B6 (as pyridoxal 5'-phosphate) Fair
  • 5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) Good
Other Ingredients Excellent

Fillers & Additives

  • Hypromellose
  • Rice Bran
  • Organic Rice Extract
  • Gellan Gum
  • Rice Flour
Efficacy Excellent

Dosage Analysis

  • Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg Effective
  • 5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) 200 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg 290%
5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) 200 mg †

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Hypromellose Safe

Forms vegetarian capsule shells. Dissolves easily in the stomach.

Rice Bran Safe

Natural filler and source of fiber.

Organic Rice Extract Generally_safe

It is added for its potential health benefits.

Gellan Gum Safe

Creates gel structure in certain supplement forms.

Rice Flour Safe

Natural bulking agent to fill capsule space. Hypoallergenic.

Brand Trust Report
NatureWise

Founded 2012 · Ashland, Oregon, USA · 35 products · naturewise.com

Certifications

7 certifications
Consumerlab Source available Primary evidence
Fda Gmp Inspections Source available Primary evidence
Nsf Gmp Source available Primary evidence
Usda Organic Source available Primary evidence
Vegan Certified Source available Primary evidence
NSF Contents Certified Supporting evidence unavailable
NSF Certified Supporting evidence unavailable

Transparency

4 claims
Third Party Testing Claim — Verified Evidence available Evidence
Testing Lab Disclosure — True Brand claim; evidence unavailable
Contains Proprietary Blend — True Brand claim; evidence unavailable

Violation History

5 incidents
Lawsuit False advertising, misrepresenting ingredients, and manipulating Amazon reviews.2023 Source available Primary source
Prop 65 Lead2020-11-13 Source available Primary source
Prop 65 Lead2020-09-14 Source available Primary source
Lawsuit Falsely advertising the dosage of curcumin in their supplement.2020 Source available Primary source
Lawsuit False advertising, including misrepresenting ingredients and manipulating Amazon reviews.2020 Source available Primary source
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Frequently Asked Questions
Is NatureWise 5-HTP Plus+, 60 Vegetarian Capsules a good supplement?

NatureWise 5-HTP Plus+, 60 Vegetarian Capsules received a product quality score of 93/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 2 active ingredients with 60 servings per container. All 5 inactive ingredients (fillers, binders, capsule materials) are rated safe — a clean formulation with no flagged additives. The manufacturer, NatureWise, holds a brand trust score of 90/100.

What are the ingredients in NatureWise 5-HTP Plus+, 60 Vegetarian Capsules?

NatureWise 5-HTP Plus+, 60 Vegetarian Capsules contains 2 active ingredients: Vitamin B6 (as pyridoxal 5'-phosphate) (5 mg), 5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) (200 mg). Notable high-dose ingredients include Vitamin B6 at 290% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is NatureWise 5-HTP Plus+, 60 Vegetarian Capsules safe to take?

GoodSupp reviewed the inactive-ingredient data available for NatureWise 5-HTP Plus+, 60 Vegetarian Capsules. All 5 inactive ingredients — including capsule materials, fillers, and binders — are currently classified as safe in GoodSupp's ingredient reference data. This label analysis cannot determine whether the product is safe for a particular person, and source labels may change. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is NatureWise a trustworthy supplement brand?

NatureWise receives a brand trust score of 90/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 2012 and headquartered in Ashland, Oregon, USA, the company offers 35 products in their lineup. Note: NatureWise has 5 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.