NatureWise 5-HTP Plus+, 30 Vegetarian Capsules supplement bottle
NatureWise

5-HTP Plus+, 30 Vegetarian Capsules Review

What We Researched
2 active ingredients analyzed · 5 inactive ingredients decoded · 7 brand certifications checked · Last updated: Aug 2026
93
Product Score Excellent
90
Brand Score Excellent

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg 290%
5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) 200 mg
Bioavailability Very Good

Absorption Rating

  • Vitamin B6 (as pyridoxal 5'-phosphate) Fair
  • 5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) Good
Other Ingredients Excellent

Fillers & Additives

  • Hypromellose
  • Rice Bran
  • Organic Rice Extract
  • Rice Flour
  • Gellan Gum
Efficacy Excellent

Dosage Analysis

  • Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg Effective
  • 5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) 200 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg 290%
5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) 200 mg

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Hypromellose Safe

Forms vegetarian capsule shells. Dissolves easily in the stomach.

Rice Bran Safe

Natural filler and source of fiber.

Organic Rice Extract Generally_safe

It is added for its potential health benefits.

Rice Flour Safe

Natural bulking agent to fill capsule space. Hypoallergenic.

Gellan Gum Safe

Creates gel structure in certain supplement forms.

Brand Trust Report
NatureWise

Founded 2012 · Ashland, Oregon, USA · 35 products · naturewise.com

Certifications

7 certifications
Consumerlab Verified Source
Fda Gmp Inspections Verified Source
Nsf Gmp Verified Source
Usda Organic Verified Source
Vegan Certified Verified Source
NSF Contents Certified Verified
NSF Certified Verified

Transparency

4 claims
Third Party Testing Claim — Verified Source
Testing Lab Disclosure — True
Contains Proprietary Blend — True

Violation History

5 incidents
Lawsuit False advertising, misrepresenting ingredients, and manipulating Amazon reviews.2023Source
Prop 65 Lead2020-11-13Source
Prop 65 Lead2020-09-14Source
Lawsuit Falsely advertising the dosage of curcumin in their supplement.2020Source
Lawsuit False advertising, including misrepresenting ingredients and manipulating Amazon reviews.2020Source
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Frequently Asked Questions
Is NatureWise 5-HTP Plus+, 30 Vegetarian Capsules a good supplement?

NatureWise 5-HTP Plus+, 30 Vegetarian Capsules received a product quality score of 93/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 2 active ingredients with 30 servings per container. Of the 5 inactive ingredients, 4 are rated safe and 0 are flagged for review. The manufacturer, NatureWise, holds a brand trust score of 90/100 with 7 verified certifications including Consumerlab, Fda Gmp Inspections, Nsf Gmp, Usda Organic.

What are the ingredients in NatureWise 5-HTP Plus+, 30 Vegetarian Capsules?

NatureWise 5-HTP Plus+, 30 Vegetarian Capsules contains 2 active ingredients: Vitamin B6 (as pyridoxal 5'-phosphate) (5 mg), 5-HTP (L-5 Hydroxy Tryptophan) (Griffonia simplicifolia) (seed) (200 mg). Notable high-dose ingredients include Vitamin B6 at 290% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is NatureWise 5-HTP Plus+, 30 Vegetarian Capsules safe to take?

NatureWise 5-HTP Plus+, 30 Vegetarian Capsules has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is NatureWise a trustworthy supplement brand?

NatureWise receives a brand trust score of 90/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 2012 and headquartered in Ashland, Oregon, USA, the company offers 35 products in their lineup. They hold 7 verified certifications including Consumerlab, Fda Gmp Inspections, Nsf Gmp, Usda Organic. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: NatureWise has 5 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.