The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg supplement bottle
The Vitamin Shoppe

5-HTP with Vitamin B6 100 mg Review

What We Researched
4 active ingredients analyzed · 4 inactive ingredients decoded · 4 brand certifications checked · Page generated: Sep 2026
75
Product Score Fair
83
Brand Score Good

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin B6 (as Pyridoxine Hydrochloride) 20 mg 1176%
Calcium (as Dicalcium Phosphate) 70 mg 5%
Phosphorus (as Dicalcium Phosphate) 54 mg 4%
5-Hydroxytryptophan (as Griffonia simplicifolia Seed Extract) 100 mg †
Bioavailability Very Good

Absorption Rating

  • Vitamin B6 (as Pyridoxine Hydrochloride) Fair
  • Calcium (as Dicalcium Phosphate) Fair
  • Phosphorus (as Dicalcium Phosphate) Good
  • 5-Hydroxytryptophan (as Griffonia simplicifolia Seed Extract) Good
Other Ingredients Excellent

Fillers & Additives

  • Microcrystalline Cellulose
  • Gelatin
  • Magnesium Stearate
  • Silicon Dioxide
Efficacy Poor

Dosage Analysis

  • Vitamin B6 (as Pyridoxine Hydrochloride) 20 mg Effective
  • Calcium (as Dicalcium Phosphate) 70 mg Under-dosed
  • Phosphorus (as Dicalcium Phosphate) 54 mg Under-dosed
  • 5-Hydroxytryptophan (as Griffonia simplicifolia Seed Extract) 100 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Vitamin B6 (as Pyridoxine Hydrochloride) 20 mg 1176%
Calcium (as Dicalcium Phosphate) 70 mg 5%
Phosphorus (as Dicalcium Phosphate) 54 mg 4%
5-Hydroxytryptophan (as Griffonia simplicifolia Seed Extract) 100 mg †

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Gelatin Safe

Forms the capsule shell that holds the supplement contents.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Silicon Dioxide Safe

Prevents clumping and ensures consistent dosing.

Brand Trust Report
The Vitamin Shoppe

Founded 1977 · Secaucus, New Jersey, U.S. · 1050 products · vitaminshoppe.com

Certifications

4 certifications
Nsf Certified For Sport Source available Primary evidence
Fda Gmp Inspections Source available Primary evidence
Usda Organic Source available Primary evidence
Non-GMO Project Verified Supporting evidence unavailable

Transparency

4 claims
Third Party Testing Claim — Verified Evidence available Evidence
Coa Availability — Verified Evidence available Evidence
Contains Proprietary Blend — True Brand claim; evidence unavailable

Violation History

6 incidents
Lawsuit Understating the sodium content of its Plnt Organic Protein Bar.2025 Source available Primary source
Prop 65 Lead2024-02-08 Source available Primary source
Lawsuit Failure to pay accurate wages and provide proper breaks.2023 Source available Primary source
Lawsuit False and misleading labeling on BodyTech glutamine supplements.2023 Source available Primary source
Recall Vthrive Bioactive Women's One-Daily Multi vitamins2020-09-24 Source available Primary source
Recall The Vitamin Shoppe Energy Formula multivitamins2020-04-16 Source available Primary source
Related Supplements
Frequently Asked Questions
Is The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg a good supplement?

The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg received a product quality score of 75/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 4 active ingredients All 4 inactive ingredients (fillers, binders, capsule materials) are rated safe — a clean formulation with no flagged additives. The manufacturer, The Vitamin Shoppe, holds a brand trust score of 83/100.

What are the ingredients in The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg?

The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg contains 4 active ingredients: Vitamin B6 (as Pyridoxine Hydrochloride) (20 mg), Calcium (as Dicalcium Phosphate) (70 mg), Phosphorus (as Dicalcium Phosphate) (54 mg), 5-Hydroxytryptophan (as Griffonia simplicifolia Seed Extract) (100 mg). Notable high-dose ingredients include Vitamin B6 at 1176% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg safe to take?

GoodSupp reviewed the inactive-ingredient data available for The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg. All 4 inactive ingredients — including capsule materials, fillers, and binders — are currently classified as safe in GoodSupp's ingredient reference data. This label analysis cannot determine whether the product is safe for a particular person, and source labels may change. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is The Vitamin Shoppe a trustworthy supplement brand?

The Vitamin Shoppe receives a brand trust score of 83/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1977 and headquartered in Secaucus, New Jersey, U.S., the company offers 1050 products in their lineup. Note: The Vitamin Shoppe has 6 historical regulatory incidents on record, which are factored into the trust score.

How much vitamin d3 should i take daily?

The optimal dosage depends on your individual health needs, age, sex, and current nutrient levels. Recommended daily amounts are established by health authorities but may vary from therapeutic doses used in clinical research. It's important to check the Supplement Facts label for the exact amount per serving and compare it against the % Daily Value. Some supplements provide mega-doses well above the Daily Value, which may not be necessary and in some cases could be harmful — particularly for fat-soluble vitamins (A, D, E, K) that accumulate in the body. GoodSupp's efficacy analysis evaluates whether a product's dosages align with clinically studied amounts. Always consult your healthcare provider for personalized dosage recommendations.

What does vitamin d do?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 150,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

How much vitamin d3 per day for a woman?

The optimal dosage depends on your individual health needs, age, sex, and current nutrient levels. Recommended daily amounts are established by health authorities but may vary from therapeutic doses used in clinical research. It's important to check the Supplement Facts label for the exact amount per serving and compare it against the % Daily Value. Some supplements provide mega-doses well above the Daily Value, which may not be necessary and in some cases could be harmful — particularly for fat-soluble vitamins (A, D, E, K) that accumulate in the body. GoodSupp's efficacy analysis evaluates whether a product's dosages align with clinically studied amounts. Always consult your healthcare provider for personalized dosage recommendations.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.