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Ortho Molecular Products Methyl B12 supplement bottle
Ortho Molecular Products

Methyl B12 Review

What We Researched
2 active ingredients analyzed · 11 inactive ingredients decoded · 5 brand certifications checked · Page generated: Sep 2026
96
Product Score Excellent
96
Brand Score Excellent

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Folate (as Quatrefolic) 1000 mcg 250%
Vitamin B12 (as Methylcobalamin) 5000 mcg 83333%
Bioavailability Excellent

Absorption Rating

  • Folate (as Quatrefolic) Good
  • Vitamin B12 (as Methylcobalamin) Good
Other Ingredients Excellent

Fillers & Additives

  • Croscarmellose Sodium
  • Sodium Stearyl Fumarate
  • Cane Sugar
  • Stearic Acid
  • Isomalt
  • Silica
  • Natural Color
  • Potassium Bicarbonate
  • Natural black cherry flavor
  • Silicon Dioxide
  • Bilberry Extract
Efficacy Very Good

Dosage Analysis

  • Folate (as Quatrefolic) 1000 mcg Effective
  • Vitamin B12 (as Methylcobalamin) 5000 mcg High

Supplement Facts

Ingredient Amount % Daily Value
Folate (as Quatrefolic) 1000 mcg 250%
Vitamin B12 (as Methylcobalamin) 5000 mcg 83333%

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Croscarmellose Sodium Safe

Helps tablets break apart and dissolve quickly in the stomach.

Sodium Stearyl Fumarate Generally_safe

It is used as a lubricant to improve the flow of powder during manufacturing.

Cane Sugar Generally_safe

It is used as a sweetener.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Isomalt Generally_safe

It provides sweetness with fewer calories than sugar.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Natural Color Generally_safe

It is used to add color to supplements.

Potassium Bicarbonate Safe

It is used as a buffering agent to adjust pH levels.

Natural black cherry flavor Unknown
Silicon Dioxide Safe

Prevents clumping and ensures consistent dosing.

Bilberry Extract Generally_safe

It is added for its antioxidant properties and potential health benefits.

Brand Trust Report
Ortho Molecular Products

Founded 1989 · Barrington, IL, USA · 233 products · orthomolecularproducts.com/

Certifications

5 certifications
Consumerlab Source available Primary evidence
Fda Gmp Inspections Source available Primary evidence
Nsf Gmp Source available Primary evidence
Usda Organic Source available Primary evidence
NSF Certified Supporting evidence unavailable

Transparency

5 claims
Third Party Testing Claim — Claimed Evidence available Evidence
In House Testing — Verified Evidence available Evidence
Testing Lab Disclosure — True Brand claim; evidence unavailable
Contains Proprietary Blend — True Brand claim; evidence unavailable

Violation History

6 incidents
Recall Fiber Powder2023-01-12 Source available Primary source
Lawsuit Patent Infringement2023 Source available Primary source
Recall Dietary Supplements2020-07-16 Source available Primary source
Recall LifeCore Chocolate and LifeCore Complete Chocolate2014-08-01 Source available Primary source
Fda Warning Making drug claims for dietary supplements such as Candicid Forte, Inflamma-bLOX, Lipitrol, Mucosagen, Prostatrol Forte, Resvoxitrol, Paracid Forte, VascuPak HTN and Lithium Orotate.2012-10-15 Source available Primary source
Prop 65 Lead2012-01-06 Source available Primary source
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Frequently Asked Questions
Is Ortho Molecular Products Methyl B12 a good supplement?

Ortho Molecular Products Methyl B12 received a product quality score of 96/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 2 active ingredients with 60 servings per container. Of the 11 inactive ingredients, 10 are rated safe and 0 ingredients are flagged for review. The manufacturer, Ortho Molecular Products, holds a brand trust score of 96/100.

What are the ingredients in Ortho Molecular Products Methyl B12?

Ortho Molecular Products Methyl B12 contains 2 active ingredients: Folate (as Quatrefolic) (1000 mcg), Vitamin B12 (as Methylcobalamin) (5000 mcg). Notable high-dose ingredients include Folate at 250% DV, Vitamin B12 at 83333% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Ortho Molecular Products Methyl B12 safe to take?

GoodSupp reviewed the inactive-ingredient data available for Ortho Molecular Products Methyl B12. This label analysis cannot determine whether the product is safe for a particular person, and source labels may change. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Ortho Molecular Products a trustworthy supplement brand?

Ortho Molecular Products receives a brand trust score of 96/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1989 and headquartered in Barrington, IL, USA, the company offers 233 products in their lineup. Note: Ortho Molecular Products has 6 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.