NaturesPlus Shot-O-B12® Sustained Release 5,000 mcg supplement bottle
NaturesPlus

Shot-O-B12® Sustained Release 5,000 mcg Review

What We Researched
1 active ingredient analyzed · 7 inactive ingredients decoded · Last updated: Aug 2026
93
Product Score Excellent
58
Brand Score Poor

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin B12 (as methylcobalamin) 5,000 mcg 208,333%
Bioavailability Excellent

Absorption Rating

  • Vitamin B12 (as methylcobalamin) Good
Other Ingredients Excellent

Fillers & Additives

  • Di-Calcium Phosphate
  • Microcrystalline Cellulose
  • Hydroxypropyl Methylcellulose
  • Stearic Acid
  • Magnesium Stearate
  • Silica
  • Natural color (beet juice) (Beta vulgaris root) and pharmaceutical glaze
Efficacy Very Good

Dosage Analysis

  • Vitamin B12 (as methylcobalamin) 5,000 mcg High

Supplement Facts

Ingredient Amount % Daily Value
Vitamin B12 (as methylcobalamin) 5,000 mcg 208,333%

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Di-Calcium Phosphate Generally_safe

It is used as a filler or source of calcium and phosphorus.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Hydroxypropyl Methylcellulose Safe

It is used as a coating for tablets and capsules.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Natural color (beet juice) (Beta vulgaris root) and pharmaceutical glaze Unknown
Brand Trust Report
NaturesPlus

Founded 1972 · Melville, New York, United States · 534 products · naturesplus.com

Transparency

3 claims
Third Party Testing Claim — Claimed
In House Testing — Claimed

Violation History

1 incident
Recall Keto Living Sugar Control Capsules2022-05-06Source
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Frequently Asked Questions
Is NaturesPlus Shot-O-B12® Sustained Release 5,000 mcg a good supplement?

NaturesPlus Shot-O-B12® Sustained Release 5,000 mcg received a product quality score of 93/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 1 active ingredients Of the 7 inactive ingredients, 5 are rated safe and 0 are flagged for review. The manufacturer, NaturesPlus, holds a brand trust score of 58/100.

What are the ingredients in NaturesPlus Shot-O-B12® Sustained Release 5,000 mcg?

NaturesPlus Shot-O-B12® Sustained Release 5,000 mcg contains 1 active ingredients: Vitamin B12 (as methylcobalamin) (5,000 mcg). Notable high-dose ingredients include Vitamin B12 at 208,333% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is NaturesPlus Shot-O-B12® Sustained Release 5,000 mcg safe to take?

NaturesPlus Shot-O-B12® Sustained Release 5,000 mcg has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is NaturesPlus a trustworthy supplement brand?

NaturesPlus receives a brand trust score of 58/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1972 and headquartered in Melville, New York, United States, the company offers 534 products in their lineup. Note: NaturesPlus has 1 historical regulatory incident on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.