Natural Factors BioCoenzymated Folate + B12 Quick-Dissolve Tablets supplement bottle
Natural Factors

BioCoenzymated Folate + B12 Quick-Dissolve Tablets Review

What We Researched
2 active ingredients analyzed · 5 inactive ingredients decoded · 5 brand certifications checked · Last updated: Aug 2026
96
Product Score Excellent
100
Brand Score Excellent

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Folate (from (6S)-5-methyltetrahydrofolate acid (MTHF), glucosamine salt, Quatrefolic®) (1000 mcg (6S) -5-MTHF] 1,700 mcg DFE 425%
Vitamin B12 (as methylcobalamin) 50 mcg 2,083%
Bioavailability Excellent

Absorption Rating

  • Folate (from (6S)-5-methyltetrahydrofolate acid (MTHF), glucosamine salt, Quatrefolic®) (1000 mcg (6S) -5-MTHF] Good
  • Vitamin B12 (as methylcobalamin) Good
Other Ingredients Excellent

Fillers & Additives

  • Microcrystalline Cellulose
  • Croscarmellose Sodium
  • Lactose
  • Vegetable Magnesium Stearate
  • Magnesium Stearate
Efficacy Very Good

Dosage Analysis

  • Folate (from (6S)-5-methyltetrahydrofolate acid (MTHF), glucosamine salt, Quatrefolic®) (1000 mcg (6S) -5-MTHF] 1,700 mcg DFE High
  • Vitamin B12 (as methylcobalamin) 50 mcg Effective

Supplement Facts

Ingredient Amount % Daily Value
Folate (from (6S)-5-methyltetrahydrofolate acid (MTHF), glucosamine salt, Quatrefolic®) (1000 mcg (6S) -5-MTHF] 1,700 mcg DFE 425%
Vitamin B12 (as methylcobalamin) 50 mcg 2,083%

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Croscarmellose Sodium Safe

Helps tablets break apart and dissolve quickly in the stomach.

Lactose Generally_safe

It is used as a filler or binder.

Vegetable Magnesium Stearate Safe

Prevents ingredients from sticking to equipment. Derived from vegetable sources.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Brand Trust Report
Natural Factors

Founded 1950 · Coquitlam, British Columbia, Canada · 832 products · naturalfactors.com

Certifications

5 certifications
B Corp Certified Verified Source
Usp Verified Verified Source
Fda Gmp Inspections Verified Source
Non Gmo Project Verified Source
Usda Organic Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

5 incidents
Prop 65 Lead2025-10-31Source
Recall Hi Potency B Complex, RevitalX, Super Multi® IRON FREE2024-07-19Source
Lawsuit Products labeled as containing glucosamine sulfate did not contain the ingredient.2021Source
Prop 65 Lead2016-01-13Source
Recall Natural Factors L-Arginine 500mg2006-04-05Source
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Frequently Asked Questions
Is Natural Factors BioCoenzymated Folate + B12 Quick-Dissolve Tablets a good supplement?

Natural Factors BioCoenzymated Folate + B12 Quick-Dissolve Tablets received a product quality score of 96/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 2 active ingredients Of the 5 inactive ingredients, 4 are rated safe and 0 are flagged for review. The manufacturer, Natural Factors, holds a brand trust score of 100/100 with 5 verified certifications including B Corp Certified, Usp Verified, Fda Gmp Inspections, Non Gmo Project.

What are the ingredients in Natural Factors BioCoenzymated Folate + B12 Quick-Dissolve Tablets?

Natural Factors BioCoenzymated Folate + B12 Quick-Dissolve Tablets contains 2 active ingredients: Folate (from (6S)-5-methyltetrahydrofolate acid (MTHF), glucosamine salt, Quatrefolic®) (1000 mcg (6S) -5-MTHF] (1,700 mcg DFE), Vitamin B12 (as methylcobalamin) (50 mcg). Notable high-dose ingredients include Folate at 425% DV, Vitamin B12 at 2,083% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Natural Factors BioCoenzymated Folate + B12 Quick-Dissolve Tablets safe to take?

Natural Factors BioCoenzymated Folate + B12 Quick-Dissolve Tablets has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Natural Factors a trustworthy supplement brand?

Natural Factors receives a brand trust score of 100/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1950 and headquartered in Coquitlam, British Columbia, Canada, the company offers 832 products in their lineup. They hold 5 verified certifications including B Corp Certified, Usp Verified, Fda Gmp Inspections, Non Gmo Project. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Natural Factors has 5 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.