Natural Factors BioCoenzymated, B5, Pantethine, 450 mg supplement bottle
Natural Factors

BioCoenzymated, B5, Pantethine, 450 mg Review

What We Researched
1 active ingredient analyzed · 45 inactive ingredients decoded · 5 brand certifications checked · Last updated: Aug 2026
100
Product Score Excellent
100
Brand Score Excellent

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Pantethine (Pantesin®) 450 mg **
Bioavailability Excellent

Absorption Rating

  • Pantethine (Pantesin®) Good
Other Ingredients Excellent

Fillers & Additives

  • Softgel (Gelatin, Glycerin, Purified Water)
  • Farm fresh factors™†
  • †active vegetables - organic kale
  • Organic alfalfa
  • Organic cilantro leaf
  • Organic parsley
  • Caperberry
  • Sprouted garlic
  • Organic artichoke
  • Organic black radish
  • Organic dandelion
  • Barley grass
  • Pepper
  • Organic celery seed
  • Organic beetroot
  • Organic tomato
  • Organic upland cress
  • Daikon
  • Red radish
  • Organic cauliflower
  • Organic cabbage
  • Organic arugula
  • Organic watercress leaf
  • Ultra fruit polyphenols - grape
  • Pomegranate
  • Strawberry
  • Organic blueberry
  • Raspberry
  • Bilberry
  • Organic indian gooseberry
  • Schizandra berry
  • Red orange
  • Organic açai berry
  • Herbals and plants - theracurmin® curcumin
  • Organic decaffeinated green tea extract
  • Organic ginger rhizome
  • Organic echinacea
  • Organic oregano
  • Organic peppermint
  • Organic spearmint
  • Whole plant sea vegetables - organic spirulina
  • Organic chlorella
  • Red algae
  • Blue green algae
  • Kelp
Efficacy Excellent

Dosage Analysis

  • Pantethine (Pantesin®) 450 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
Pantethine (Pantesin®) 450 mg **

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Softgel (Gelatin, Glycerin, Purified Water) Generally_safe

It encapsulates the supplement ingredients for easy swallowing and delivery.

Farm fresh factors™† Unknown
†active vegetables - organic kale Unknown
Organic alfalfa Unknown
Organic cilantro leaf Unknown
Organic parsley Unknown
Caperberry Unknown
Sprouted garlic Unknown
Organic artichoke Unknown
Organic black radish Unknown
Organic dandelion Unknown
Barley grass Unknown
Pepper Unknown
Organic celery seed Unknown
Organic beetroot Unknown
Organic tomato Unknown
Organic upland cress Unknown
Daikon Unknown
Red radish Unknown
Organic cauliflower Unknown
Organic cabbage Unknown
Organic arugula Unknown
Organic watercress leaf Unknown
Ultra fruit polyphenols - grape Unknown
Pomegranate Unknown
Strawberry Unknown
Organic blueberry Unknown
Raspberry Unknown
Bilberry Unknown
Organic indian gooseberry Unknown
Schizandra berry Unknown
Red orange Unknown
Organic açai berry Unknown
Herbals and plants - theracurmin® curcumin Unknown
Organic decaffeinated green tea extract Unknown
Organic ginger rhizome Unknown
Organic echinacea Unknown
Organic oregano Unknown
Organic peppermint Unknown
Organic spearmint Unknown
Whole plant sea vegetables - organic spirulina Unknown
Organic chlorella Unknown
Red algae Unknown
Blue green algae Unknown
Kelp Generally_safe

It is included as a source of iodine.

Brand Trust Report
Natural Factors

Founded 1950 · Coquitlam, British Columbia, Canada · 832 products · naturalfactors.com

Certifications

5 certifications
B Corp Certified Verified Source
Usp Verified Verified Source
Fda Gmp Inspections Verified Source
Non Gmo Project Verified Source
Usda Organic Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

5 incidents
Prop 65 Lead2025-10-31Source
Recall Hi Potency B Complex, RevitalX, Super Multi® IRON FREE2024-07-19Source
Lawsuit Products labeled as containing glucosamine sulfate did not contain the ingredient.2021Source
Prop 65 Lead2016-01-13Source
Recall Natural Factors L-Arginine 500mg2006-04-05Source
Related Supplements
Frequently Asked Questions
Is Natural Factors BioCoenzymated, B5 a good supplement?

Natural Factors BioCoenzymated, B5, Pantethine, 450 mg received a product quality score of 100/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 1 active ingredients Of the 45 inactive ingredients, 0 are rated safe and 0 are flagged for review. The manufacturer, Natural Factors, holds a brand trust score of 100/100 with 5 verified certifications including B Corp Certified, Usp Verified, Fda Gmp Inspections, Non Gmo Project.

What are the ingredients in Natural Factors BioCoenzymated, B5?

Natural Factors BioCoenzymated, B5 contains 1 active ingredients: Pantethine (Pantesin®) (450 mg). Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Natural Factors BioCoenzymated, B5 safe to take?

Natural Factors BioCoenzymated, B5, Pantethine, 450 mg has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Natural Factors a trustworthy supplement brand?

Natural Factors receives a brand trust score of 100/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1950 and headquartered in Coquitlam, British Columbia, Canada, the company offers 832 products in their lineup. They hold 5 verified certifications including B Corp Certified, Usp Verified, Fda Gmp Inspections, Non Gmo Project. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Natural Factors has 5 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.