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Metagenics Symphora supplement bottle
Metagenics

Symphora Review

What We Researched
4 active ingredients analyzed · 6 inactive ingredients decoded · 8 brand certifications checked · Page generated: Sep 2026
93
Product Score Excellent
100
Brand Score Excellent

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin D (as Cholecalciferol) 800 IU 200%
Folate (as 5-Methyl Tetrahydrofolate) 800 mcg 200%
Vitamin B12 (as Methylcobalamin) 1000 mcg 16667%
Dehydroepiandrosterone 50 mg †
Bioavailability Very Good

Absorption Rating

  • Vitamin D (as Cholecalciferol) Good
  • Folate (as 5-Methyl Tetrahydrofolate) Fair
  • Vitamin B12 (as Methylcobalamin) Good
  • Dehydroepiandrosterone Fair
Other Ingredients Excellent

Fillers & Additives

  • Microcrystalline Cellulose
  • Cellulose
  • Croscarmellose Sodium
  • Stearic Acid
  • Silica
  • Coating
Efficacy Excellent

Dosage Analysis

  • Vitamin D (as Cholecalciferol) 800 IU Effective
  • Folate (as 5-Methyl Tetrahydrofolate) 800 mcg Effective
  • Vitamin B12 (as Methylcobalamin) 1000 mcg Effective
  • Dehydroepiandrosterone 50 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
Vitamin D (as Cholecalciferol) 800 IU 200%
Folate (as 5-Methyl Tetrahydrofolate) 800 mcg 200%
Vitamin B12 (as Methylcobalamin) 1000 mcg 16667%
Dehydroepiandrosterone 50 mg †

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Cellulose Safe

Provides bulk and structure in tablets and capsules.

Croscarmellose Sodium Safe

Helps tablets break apart and dissolve quickly in the stomach.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Coating Unknown
Brand Trust Report
Metagenics

Founded 1983 · Aliso Viejo, California, United States · 429 products · metagenics.com

Certifications

8 certifications
B Corp Certified Source available Primary evidence
Gluten Free Gfco Source available Primary evidence
Non Gmo Project Source available Primary evidence
Fda Gmp Inspections Source available Primary evidence
Nsf Gmp Source available Primary evidence
Usp Verified Source available Primary evidence
NSF Certified Supporting evidence unavailable
Gluten-Free Certified Supporting evidence unavailable

Transparency

6 claims
Third Party Testing Claim — Verified Evidence available Evidence
Coa Availability — Claimed Evidence available Evidence
In House Testing — Verified Evidence available Evidence
Testing Lab Disclosure — True Brand claim; evidence unavailable
Contains Proprietary Blend — True Brand claim; evidence unavailable

Violation History

3 incidents
Fda Warning A structure/function claim for 'Metagenics HerWellness Naturally Balanced' was deemed by the FDA to suggest the product is intended for use as a drug.2025-02-07 Source available Primary source
Prop 65 Lead2019-05-30 Source available Primary source
Fda Warning Mislabeling of 14 products as medical foods and making unapproved new drug claims.2013-08-13 Source available Primary source
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Frequently Asked Questions
Is Metagenics Symphora a good supplement?

Metagenics Symphora received a product quality score of 93/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 4 active ingredients with 30 servings per container. Of the 6 inactive ingredients, 5 are rated safe and 0 ingredients are flagged for review. The manufacturer, Metagenics, holds a brand trust score of 100/100.

What are the ingredients in Metagenics Symphora?

Metagenics Symphora contains 4 active ingredients: Vitamin D (as Cholecalciferol) (800 IU), Folate (as 5-Methyl Tetrahydrofolate) (800 mcg), Vitamin B12 (as Methylcobalamin) (1000 mcg), Dehydroepiandrosterone (50 mg). Notable high-dose ingredients include Vitamin B12 at 16667% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Metagenics Symphora safe to take?

GoodSupp reviewed the inactive-ingredient data available for Metagenics Symphora. This label analysis cannot determine whether the product is safe for a particular person, and source labels may change. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Metagenics a trustworthy supplement brand?

Metagenics receives a brand trust score of 100/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1983 and headquartered in Aliso Viejo, California, United States, the company offers 429 products in their lineup. Note: Metagenics has 3 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.