Doctor's Best SAM-e, 400 mg, 60 Enteric Coated Tablets supplement bottle
Doctor's Best

SAM-e, 400 mg, 60 Enteric Coated Tablets

What We Researched
1 active ingredient analyzed · 13 inactive ingredients decoded · 1 brand certification checked · 3 retailers compared · Last updated: Mar 2026
75
Product Score Fair
61
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
SAM-e( S-Adenosyl Methionine disulfate p-toluensulfonate)(Adonat®) 400 mg
Bioavailability Excellent

Absorption Rating

  • SAM-e( S-Adenosyl Methionine disulfate p-toluensulfonate)(Adonat®) Good
Other Ingredients Poor

Fillers & Additives

  • Cellulose Gel
  • Methacrylic Acid Copolymer
  • Compritol 888ATO
  • Talc High
  • Triethyl Citrate
  • Titanium Dioxide High
  • Magnesium Stearate
  • Mannitol
  • Glycerol Palmitostearate
  • Silica
  • Medium Chain Triglycerides
  • Sodium Starch Glycolate
  • Iron Oxide
Efficacy Excellent

Dosage Analysis

  • SAM-e( S-Adenosyl Methionine disulfate p-toluensulfonate)(Adonat®) 400 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
SAM-e( S-Adenosyl Methionine disulfate p-toluensulfonate)(Adonat®) 400 mg

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Cellulose Gel Generally_safe

It is used as a thickening agent to improve the texture of supplements.

Methacrylic Acid Copolymer Generally_safe

It is added to provide a protective coating or to control the release of ingredients.

Compritol 888ATO Unknown
Talc Avoid

It is used to improve powder flow and prevent clumping.

Triethyl Citrate Generally_safe

It is used as a plasticizer or solvent.

Titanium Dioxide Caution

Used as a whitening agent in tablet coatings and capsules.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Mannitol Generally_safe

It is used as a sweetener, filler, and flow agent.

Glycerol Palmitostearate Unknown
Silica Safe

Prevents ingredients from clumping and improves powder flow.

Medium Chain Triglycerides Safe

Enhances absorption of fat-soluble vitamins.

Sodium Starch Glycolate Safe

Helps tablets break apart quickly for faster absorption.

Iron Oxide Unknown

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$51$50$49$48$47 Mar 12 $48.99$48.99
iHerb
Vitacost

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Doctor's Best

Founded 1990 · Tustin, California, USA · 186 products · doctorsbest.com

Certifications

1 certification
Fda Gmp Inspections Verified Source

Transparency

2 claims
Third Party Testing Claim — Claimed Source

Violation History

1 incident
Recall Red Yeast Rice2014-06-26Source
Related Supplements
Frequently Asked Questions
Is Doctor's Best SAM-e, 400 mg a good supplement?

Doctor's Best SAM-e, 400 mg, 60 Enteric Coated Tablets received a product quality score of 75/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 1 active ingredients with 60 servings per container. Of the 13 inactive ingredients, 4 are rated safe and 1 are flagged for review. The manufacturer, Doctor's Best, holds a brand trust score of 61/100 with 1 verified certifications including Fda Gmp Inspections.

What are the ingredients in Doctor's Best SAM-e, 400 mg?

Doctor's Best SAM-e, 400 mg contains 1 active ingredients: SAM-e( S-Adenosyl Methionine disulfate p-toluensulfonate)(Adonat®) (400 mg). Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Doctor's Best SAM-e, 400 mg safe to take?

Doctor's Best SAM-e, 400 mg, 60 Enteric Coated Tablets has been analyzed for ingredient safety across all its components. Of 13 inactive ingredients, 4 are rated safe. 1 ingredient is flagged for review: Titanium Dioxide. 'Caution' doesn't mean dangerous — it indicates the ingredient has some considerations worth being aware of, such as potential sensitivities or ongoing research. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Doctor's Best a trustworthy supplement brand?

Doctor's Best receives a brand trust score of 61/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1990 and headquartered in Tustin, California, USA, the company offers 186 products in their lineup. They hold 1 verified certifications including Fda Gmp Inspections. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Doctor's Best has 1 historical regulatory incident on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.