Doctor's Best SAM-e, 200 mg, 60 Enteric Coated Tablets supplement bottle
Doctor's Best

SAM-e, 200 mg, 60 Enteric Coated Tablets Review

What We Researched
1 active ingredient analyzed · 12 inactive ingredients decoded · 1 brand certification checked · Last updated: Aug 2026
100
Product Score Excellent
61
Brand Score Fair

Two independent scores — the product and the brand behind it, never blended into one number. See our methodology.

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
SAM-e(S-Adenosyl-L-Methionine disulfate p-toluensulfonate) (Adonat®) 200 mg †
Bioavailability Excellent

Absorption Rating

  • SAM-e(S-Adenosyl-L-Methionine disulfate p-toluensulfonate) (Adonat®) Good
Other Ingredients Excellent

Fillers & Additives

  • Magnesium Silicate
  • Sodium Alginate
  • Microcrystalline Cellulose
  • Arginine
  • Vegetable Magnesium Stearate
  • Magnesium Stearate
  • Stearic Acid
  • Magnesium Hydroxide
  • Calcium oxide
  • Shellac
  • Silica
  • Glycerol
Efficacy Excellent

Dosage Analysis

  • SAM-e(S-Adenosyl-L-Methionine disulfate p-toluensulfonate) (Adonat®) 200 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
SAM-e(S-Adenosyl-L-Methionine disulfate p-toluensulfonate) (Adonat®) 200 mg †

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Magnesium Silicate Generally_safe

It is used to improve powder flow and prevent clumping.

Sodium Alginate Safe

It is used as a thickening agent and stabilizer.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Arginine Safe

It is used for its potential benefits related to blood flow and muscle function.

Vegetable Magnesium Stearate Safe

Prevents ingredients from sticking to equipment. Derived from vegetable sources.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Magnesium Hydroxide Generally_safe

It is used to provide magnesium.

Calcium oxide Unknown
Shellac Safe

Used as an enteric coating to protect supplements from stomach acid.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Glycerol Safe

It is used to retain moisture and dissolve ingredients.

Brand Trust Report
Doctor's Best

Founded 1990 · Tustin, California, USA · 351 products · doctorsbest.com

Certifications

1 certification
Fda Gmp Inspections Verified Source

Transparency

2 claims
Third Party Testing Claim — Claimed Source

Violation History

3 incidents
Lawsuit False advertising and mislabeling of glucosamine supplements.2022Source
Recall Red Yeast Rice2014-06-26Source
Recall Red Yeast Rice 600 mg Capsules, 120-count bottles2014-06-24Source
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Frequently Asked Questions
Is Doctor's Best SAM-e, 200 mg a good supplement?

Doctor's Best SAM-e, 200 mg, 60 Enteric Coated Tablets received a product quality score of 100/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 1 active ingredients with 60 servings per container. Of the 12 inactive ingredients, 9 are rated safe and 0 are flagged for review. The manufacturer, Doctor's Best, holds a brand trust score of 61/100 with 1 verified certifications including Fda Gmp Inspections.

What are the ingredients in Doctor's Best SAM-e, 200 mg?

Doctor's Best SAM-e, 200 mg contains 1 active ingredients: SAM-e(S-Adenosyl-L-Methionine disulfate p-toluensulfonate) (Adonat®) (200 mg). Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Doctor's Best SAM-e, 200 mg safe to take?

Doctor's Best SAM-e, 200 mg, 60 Enteric Coated Tablets has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Doctor's Best a trustworthy supplement brand?

Doctor's Best receives a brand trust score of 61/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1990 and headquartered in Tustin, California, USA, the company offers 351 products in their lineup. They hold 1 verified certifications including Fda Gmp Inspections. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Doctor's Best has 3 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.