Sucralose

Generally Safe SweetenerSynthetic

Sucralose is a synthetic sweetener used in dietary supplements. Safety rating: Generally Safe. It is generally considered safe for most people at standard doses. Found in 20 supplements in the GoodSupp database. An artificial sweetener approximately 600 times sweeter than sugar.

20 Products use this
Generally Safe Safety rating
Sweetener Category
No Natural origin

Safety Verdict: Generally Safe

FDA approved; some studies suggest gut microbiome effects at very high doses

What is Sucralose?

An artificial sweetener approximately 600 times sweeter than sugar.

Common Names Sucralose, Splenda
Type Sweetener
Origin Synthetic / Manufactured
Safety Rating Generally Safe

Why is Sucralose used in supplements?

Adds sweetness to chewables, gummies, and powdered supplements without calories.

Role in supplements: Sweetener — adds sweetness to chewable or liquid supplements without adding significant calories.

Should you be concerned about Sucralose?

Generally no. Sucralose is considered safe for most people at typical supplement doses. Some individuals may want to be aware of minor sensitivities.

FDA approved; some studies suggest gut microbiome effects at very high doses

Low risk. Generally safe for most people in supplement amounts.

Top-rated products containing Sucralose

These 20 highest-scoring supplements in our database use Sucralose.

Nutricost Creatine Monohydrate Fruit Punch
Nutricost Creatine Monohydrate Fruit Punch
Product 100 Brand N/A
Nutricost Creatine Monohydrate Blue Raspberry
Nutricost Creatine Monohydrate Blue Raspberry
Product 100 Brand N/A
Nutricost L-Glutamine, Fruit Punch
Nutricost L-Glutamine, Fruit Punch
Product 100 Brand N/A
Nature's Bounty Biotin Strawberry 5,000 mcg Quick Dissolve Tablets
Nature's Bounty Biotin Strawberry 5,000 mcg Quick Dissolve Tablets
Product 100 Brand N/A
C4 / Cellucor COR-Performance® Creatine, Blue Raspberry
C4 / Cellucor COR-Performance® Creatine, Blue Raspberry
Product 100 Brand N/A
Nutricost Creatine Monohydrate Pineapple Mango
Nutricost Creatine Monohydrate Pineapple Mango
Product 100 Brand N/A
Nutricost Creatine Monohydrate Fruit Punch
Nutricost Creatine Monohydrate Fruit Punch
Product 100 Brand N/A
Nutricost Creatine Monohydrate Watermelon
Nutricost Creatine Monohydrate Watermelon
Product 100 Brand N/A
Nutricost Creatine Monohydrate Mandarin Orange
Nutricost Creatine Monohydrate Mandarin Orange
Product 100 Brand N/A
Nutricost Performance, Creatine Monohydrate, Grape
Nutricost Performance, Creatine Monohydrate, Grape
Product 100 Brand N/A
Nutricost Creatine Monohydrate Mandarin Orange
Nutricost Creatine Monohydrate Mandarin Orange
Product 100 Brand N/A
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Product 100 Brand N/A
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Product 100 Brand N/A
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Product 100 Brand N/A
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Nutricost Creatine Monohydrate Variety Pack 5.2- 6.7 g
Product 100 Brand N/A
Nutricost Performance, Creatine + Aminos, Grape
Nutricost Performance, Creatine + Aminos, Grape
Product 100 Brand N/A
Nutrex Research Creatine Monohydrate, Fruit Punch
Nutrex Research Creatine Monohydrate, Fruit Punch
Product 100 Brand N/A
Nutrex Research Creatine Monohydrate, Fruit Punch
Nutrex Research Creatine Monohydrate, Fruit Punch
Product 100 Brand N/A
Nutricost Creatine Monohydrate Red Alert Citrus Cherry
Nutricost Creatine Monohydrate Red Alert Citrus Cherry
Product 100 Brand N/A
Nutricost L-Citrulline Malate 2:1, Blue Raspberry
Nutricost L-Citrulline Malate 2:1, Blue Raspberry
Product 100 Brand N/A
Related Ingredients
Acesulfame K Generally Safe Acesulfame Potassium Generally Safe Acesulfame-K Generally Safe Acesulfame-Potassium Generally Safe Allulose Generally Safe Apple Juice Concentrate Safe Beet Sugar Generally Safe Brown Rice Syrup Generally Safe
Frequently Asked Questions
Is Sucralose safe in supplements?

Sucralose is rated generally safe for most people at amounts commonly found in supplements. While the overall safety profile is favorable, some individuals may experience minor sensitivities. FDA approved; some studies suggest gut microbiome effects at very high doses In GoodSupp's database, 20 products contain this ingredient. Consult your healthcare provider if you have specific concerns.

What is Sucralose and why is it in my supplement?

An artificial sweetener approximately 600 times sweeter than sugar. As a sweetener, it improves the taste of chewable, liquid, or powder supplements without adding significant calories. It appears in 20 products in the GoodSupp database.

Is Sucralose natural or synthetic?

Sucralose is synthetically produced, meaning it is manufactured through chemical processes rather than directly extracted from natural sources. Synthetic ingredients are extremely common in supplements and are not inherently less safe than natural alternatives. In many cases, synthetic production allows for higher purity and more consistent quality. The FDA regulates both natural and synthetic supplement ingredients under the same safety standards. GoodSupp rates ingredients based on their actual safety data regardless of whether they're natural or synthetic.

Is sucralose a carcinogen?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 150,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records — read our methodology. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.