Thorne Advanced Digestive Enzymes, 180 Capsules supplement bottle
Thorne

Advanced Digestive Enzymes, 180 Capsules

What We Researched
5 active ingredients analyzed · 3 inactive ingredients decoded · 4 brand certifications checked · 3 retailers compared · Last updated: Mar 2026
65
Product Score Fair
90
Brand Score Excellent

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Betaine Hydrochloride 480 mg *
L-Glutamic Acid Hydrochloride 480 mg *
Pancreatin (Porcine) † 140 mg *
Ox Bile concentrate 80 mg *
Pepsin (Porcine) 70 mg *
Bioavailability Good

Absorption Rating

  • Betaine Hydrochloride Good
  • L-Glutamic Acid Hydrochloride Fair
  • Pancreatin (Porcine) † Fair
  • Ox Bile concentrate Fair
  • Pepsin (Porcine) Fair
Other Ingredients Excellent

Fillers & Additives

  • Hypromellose (Derived from Cellulose) Capsule
  • Leucine
  • Silicon Dioxide
Efficacy Very Poor

Dosage Analysis

  • Betaine Hydrochloride 480 mg Under-dosed
  • L-Glutamic Acid Hydrochloride 480 mg Under-dosed
  • Pancreatin (Porcine) † 140 mg Under-dosed
  • Ox Bile concentrate 80 mg Under-dosed
  • Pepsin (Porcine) 70 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Betaine Hydrochloride 480 mg *
L-Glutamic Acid Hydrochloride 480 mg *
Pancreatin (Porcine) † 140 mg *
Ox Bile concentrate 80 mg *
Pepsin (Porcine) 70 mg *

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Hypromellose (Derived from Cellulose) Capsule Safe

It is used to encapsulate supplement ingredients.

Leucine Safe

It is used for its potential muscle-building and recovery benefits.

Silicon Dioxide Safe

Prevents clumping and ensures consistent dosing.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$58$57$56$55$54 Mar 12 $56.00
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Thorne

Founded 1984 · New York, NY, United States · 161 products · thorne.com

Certifications

4 certifications
Consumerlab Verified
Nsf Certified For Sport Verified Source
Nsf Gmp Verified Source
Fda Gmp Inspections Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

2 incidents
Recall Captomer, Captomer-2502014-06-12Source
Prop 65 Lead2013-12-13Source
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Frequently Asked Questions
Is Thorne Advanced Digestive Enzymes, 180 Capsules a good supplement?

Thorne Advanced Digestive Enzymes, 180 Capsules received a product quality score of 65/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 5 active ingredients with 90 servings per container. All 3 inactive ingredients (fillers, binders, capsule materials) are rated safe — a clean formulation with no flagged additives. The manufacturer, Thorne, holds a brand trust score of 90/100 with 4 verified certifications including Consumerlab, Nsf Certified For Sport, Nsf Gmp, Fda Gmp Inspections.

What are the ingredients in Thorne Advanced Digestive Enzymes, 180 Capsules?

Thorne Advanced Digestive Enzymes, 180 Capsules contains 5 active ingredients: Betaine Hydrochloride (480 mg), L-Glutamic Acid Hydrochloride (480 mg), Pancreatin (Porcine) † (140 mg), Ox Bile concentrate (80 mg), Pepsin (Porcine) (70 mg). Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Thorne Advanced Digestive Enzymes, 180 Capsules safe to take?

Thorne Advanced Digestive Enzymes, 180 Capsules has been analyzed for ingredient safety across all its components. All 3 inactive ingredients — including capsule materials, fillers, and binders — are rated safe based on regulatory data and published safety research. This is a clean formulation with no controversial additives. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Thorne a trustworthy supplement brand?

Thorne receives a brand trust score of 90/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1984 and headquartered in New York, NY, United States, the company offers 161 products in their lineup. They hold 4 verified certifications including Consumerlab, Nsf Certified For Sport, Nsf Gmp, Fda Gmp Inspections. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Thorne has 2 historical regulatory incidents on record, which are factored into the trust score.

When to take digestive enzymes?

Timing can affect how well your body absorbs and utilizes supplements. As a general rule: fat-soluble vitamins (A, D, E, K) and omega-3s are best taken with meals containing fat. Water-soluble vitamins (B vitamins, vitamin C) can be taken anytime but are often recommended with breakfast. Minerals like calcium and magnesium may be better absorbed when split between meals. Iron absorbs best on an empty stomach but can cause nausea — taking it with vitamin C improves absorption while reducing stomach upset. Probiotics are often recommended on an empty stomach (before breakfast) for optimal survival through stomach acid. Consistency matters more than perfect timing — taking supplements at the same time each day helps build a reliable habit.

Do digestive enzymes make you poop more?

The effects of supplements on the body vary based on the specific ingredients, dosages, and individual factors. Quality clinical research is the best guide for understanding what supplements actually do versus marketing claims. Be cautious of products that promise dramatic results — legitimate supplements support health gradually, not overnight. Checking the ingredient label, understanding the dosages, and reviewing the scientific evidence are essential steps before starting any supplement. GoodSupp evaluates over 250,000 products based on published research and evidence-based criteria.

Do digestive enzymes help with bloating?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.