NaturesPlus Mega-Stress Sustained Release supplement bottle
NaturesPlus

Mega-Stress Sustained Release

What We Researched
17 active ingredients analyzed · 13 inactive ingredients decoded · 1 retailer compared · Last updated: Mar 2026
84
Product Score Good
59
Brand Score Poor

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin C (as Ascorbic Acid) 500 mg 556%
Thiamine (as Thiamine Hydrochloride, Vitamin B1) 60 mg 5000%
Riboflavin (as Vitamin B2) 60 mg 4615%
Niacin (as Niacinamide) 125 mg NE 781%
Vitamin B6 (as Pyridoxine Hydrochloride) 100 mg 5882%
Folate (as Calcium L-5-Methyltetrahydrofolate) 667 mcg DFE 167%
Vitamin B12 (as Methylcobalamin) 250 mcg 10417%
Biotin 75 mcg 250%
Pantothenic Acid (as Calcium Pantothenate) 200 mg 4000%
Choline (as Choline Bitartrate) 32 mg 6%
Calcium (as Calcium Amino Acid Chelate) 100 mg 8%
Magnesium (as Magnesium Amino Acid Chelate) 50 mg 12%
Zinc (as Zinc Amino Acid Chelate) 25 mg 227%
Inositol 100 mg
Valerian 50 mg
Para-Aminobenzoic Acid 30 mg
Chamomile 25 mg
Bioavailability Very Good

Absorption Rating

  • Vitamin C (as Ascorbic Acid) Fair
  • Thiamine (as Thiamine Hydrochloride, Vitamin B1) Fair
  • Riboflavin (as Vitamin B2) Good
  • Niacin (as Niacinamide) Good
  • Vitamin B6 (as Pyridoxine Hydrochloride) Fair
  • Folate (as Calcium L-5-Methyltetrahydrofolate) Good
  • Vitamin B12 (as Methylcobalamin) Good
  • Biotin Good
  • Pantothenic Acid (as Calcium Pantothenate) Good
  • Choline (as Choline Bitartrate) Poor
  • Calcium (as Calcium Amino Acid Chelate) Good
  • Magnesium (as Magnesium Amino Acid Chelate) Good
  • Zinc (as Zinc Amino Acid Chelate) Fair
  • Inositol Good
  • Valerian Good
  • Para-Aminobenzoic Acid Good
  • Chamomile Fair
Other Ingredients Excellent

Fillers & Additives

  • Calcium Carbonate
  • Microcrystalline Cellulose
  • Dicalcium Phosphate
  • Stearic Acid
  • Magnesium Oxide
  • Zinc Sulfate
  • Magnesium Stearate
  • Hydroxypropyl Methylcellulose
  • Silica
  • Rose Hip
  • isolated Soy Protein
  • Rice
  • Pharmaceutical Glaze
Efficacy Fair

Dosage Analysis

  • Vitamin C (as Ascorbic Acid) 500 mg Effective
  • Thiamine (as Thiamine Hydrochloride, Vitamin B1) 60 mg Effective
  • Riboflavin (as Vitamin B2) 60 mg Effective
  • Niacin (as Niacinamide) 125 mg NE High
  • Vitamin B6 (as Pyridoxine Hydrochloride) 100 mg Effective
  • Folate (as Calcium L-5-Methyltetrahydrofolate) 667 mcg DFE Effective
  • Vitamin B12 (as Methylcobalamin) 250 mcg Effective
  • Biotin 75 mcg Effective
  • Pantothenic Acid (as Calcium Pantothenate) 200 mg Effective
  • Choline (as Choline Bitartrate) 32 mg Under-dosed
  • Calcium (as Calcium Amino Acid Chelate) 100 mg Under-dosed
  • Magnesium (as Magnesium Amino Acid Chelate) 50 mg Under-dosed
  • Zinc (as Zinc Amino Acid Chelate) 25 mg Effective
  • Inositol 100 mg Under-dosed
  • Valerian 50 mg Under-dosed
  • Para-Aminobenzoic Acid 30 mg Under-dosed
  • Chamomile 25 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Vitamin C (as Ascorbic Acid) 500 mg 556%
Thiamine (as Thiamine Hydrochloride, Vitamin B1) 60 mg 5000%
Riboflavin (as Vitamin B2) 60 mg 4615%
Niacin (as Niacinamide) 125 mg NE 781%
Vitamin B6 (as Pyridoxine Hydrochloride) 100 mg 5882%
Folate (as Calcium L-5-Methyltetrahydrofolate) 667 mcg DFE 167%
Vitamin B12 (as Methylcobalamin) 250 mcg 10417%
Biotin 75 mcg 250%
Pantothenic Acid (as Calcium Pantothenate) 200 mg 4000%
Choline (as Choline Bitartrate) 32 mg 6%
Calcium (as Calcium Amino Acid Chelate) 100 mg 8%
Magnesium (as Magnesium Amino Acid Chelate) 50 mg 12%
Zinc (as Zinc Amino Acid Chelate) 25 mg 227%
Inositol 100 mg
Valerian 50 mg
Para-Aminobenzoic Acid 30 mg
Chamomile 25 mg

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Calcium Carbonate Safe

Acts as a filler and provides supplemental calcium.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Dicalcium Phosphate Safe

Serves as both a filler and a supplemental source of calcium and phosphorus.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Magnesium Oxide Generally_safe

It is used to provide magnesium, an essential mineral.

Zinc Sulfate Generally_safe

It is used to supplement zinc intake.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Hydroxypropyl Methylcellulose Safe

It is used as a coating for tablets and capsules.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Rose Hip Unknown
isolated Soy Protein Unknown
Rice Unknown
Pharmaceutical Glaze Generally_safe

It is used to coat tablets or capsules for easier swallowing or controlled release.

Price Comparison

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
NaturesPlus

Founded 1972 · Melville, New York, United States · 420 products · naturesplus.com

Transparency

3 claims
Third Party Testing Claim — Claimed
In House Testing — Claimed

Violation History

1 incident
Recall Keto Living Sugar Control Capsules2022-05-06Source
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Frequently Asked Questions
Is NaturesPlus Mega-Stress Sustained Release a good supplement?

NaturesPlus Mega-Stress Sustained Release received a product quality score of 84/100 in GoodSupp's independent analysis, indicating strong overall quality. The product contains 17 active ingredients with 60 servings per container. Of the 13 inactive ingredients, 7 are rated safe and 0 are flagged for review. The manufacturer, NaturesPlus, holds a brand trust score of 59/100.

What are the ingredients in NaturesPlus Mega-Stress Sustained Release?

NaturesPlus Mega-Stress Sustained Release contains 17 active ingredients: Vitamin C (as Ascorbic Acid) (500 mg), Thiamine (as Thiamine Hydrochloride, Vitamin B1) (60 mg), Riboflavin (as Vitamin B2) (60 mg), Niacin (as Niacinamide) (125 mg NE), Vitamin B6 (as Pyridoxine Hydrochloride) (100 mg), Folate (as Calcium L-5-Methyltetrahydrofolate) (667 mcg DFE), and 11 more. Notable high-dose ingredients include Vitamin C at 556% DV, Thiamine at 5000% DV, Riboflavin at 4615% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is NaturesPlus Mega-Stress Sustained Release safe to take?

NaturesPlus Mega-Stress Sustained Release has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is NaturesPlus a trustworthy supplement brand?

NaturesPlus receives a brand trust score of 59/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1972 and headquartered in Melville, New York, United States, the company offers 420 products in their lineup. Note: NaturesPlus has 1 historical regulatory incident on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.