Natural Factors Ultimate Probiotic 12-12 Formula, 12 billion cells, 60 Vegetarian Capsules supplement bottle
Natural Factors

Ultimate Probiotic 12-12 Formula, 12 billion cells, 60 Vegetarian Capsules

What We Researched
14 active ingredients analyzed · 6 inactive ingredients decoded · 5 brand certifications checked · 3 retailers compared · Last updated: Mar 2026
84
Product Score Good
88
Brand Score Good

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Proprietary Synergistic Blend:
Total Active Cell Count 12 billion
Lactobacillus Casei 3 billion
Lactobacillus Rhamnosus 1.44 billion
Lactobacillus Rhamnosus (B) 1.2 billion
Lactobacillus Acidophilus 1.2 billion
Bifidobacterium Breve 1.2 billion
Bifidobacterium Longum 1.2 billion
Lactobacillus Plantarum 1.2 billion
Bifidobacterium Bifidum 0.6 billion
Lactobacillus fermentum 0.6 billion
Bifidobacterium Lactis 0.12 billion
Lactobacillus Paracasei 0.12 billion
Lactobacillus Salivarius 0.12 billion
Bioavailability Very Good

Absorption Rating

  • Proprietary Synergistic Blend: Fair
  • Lactobacillus Casei Good
  • Lactobacillus Rhamnosus Good
  • Lactobacillus Rhamnosus (B) Good
  • Lactobacillus Acidophilus Good
  • Bifidobacterium Breve Good
  • Bifidobacterium Longum Good
  • Lactobacillus Plantarum Good
  • Bifidobacterium Bifidum Fair
  • Lactobacillus fermentum Good
  • Bifidobacterium Lactis Good
  • Lactobacillus Paracasei Good
  • Lactobacillus Salivarius Fair
Other Ingredients Excellent

Fillers & Additives

  • Maltodextrin
  • Fos (fructooligosaccharides) inulin
  • Vegetable capsule (carbohydrate gum [cellulose], purified water)
  • Magnesium Stearate (Vegetable Grade)
  • Silica
  • Ascorbic Acid
Efficacy Fair

Dosage Analysis

  • Lactobacillus Casei 3 billion Effective
  • Lactobacillus Rhamnosus 1.44 billion Effective
  • Lactobacillus Rhamnosus (B) 1.2 billion Effective
  • Lactobacillus Acidophilus 1.2 billion Effective
  • Bifidobacterium Breve 1.2 billion Effective
  • Bifidobacterium Longum 1.2 billion Effective
  • Lactobacillus Plantarum 1.2 billion Effective
  • Bifidobacterium Bifidum 0.6 billion Under-dosed
  • Lactobacillus fermentum 0.6 billion Under-dosed
  • Bifidobacterium Lactis 0.12 billion Under-dosed
  • Lactobacillus Paracasei 0.12 billion Under-dosed
  • Lactobacillus Salivarius 0.12 billion Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Proprietary Synergistic Blend:
Total Active Cell Count 12 billion
Lactobacillus Casei 3 billion
Lactobacillus Rhamnosus 1.44 billion
Lactobacillus Rhamnosus (B) 1.2 billion
Lactobacillus Acidophilus 1.2 billion
Bifidobacterium Breve 1.2 billion
Bifidobacterium Longum 1.2 billion
Lactobacillus Plantarum 1.2 billion
Bifidobacterium Bifidum 0.6 billion
Lactobacillus fermentum 0.6 billion
Bifidobacterium Lactis 0.12 billion
Lactobacillus Paracasei 0.12 billion
Lactobacillus Salivarius 0.12 billion

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Maltodextrin Generally_safe

Helps carry and stabilize active ingredients. Provides bulk.

Fos (fructooligosaccharides) inulin Unknown
Vegetable capsule (carbohydrate gum [cellulose], purified water) Unknown
Magnesium Stearate (Vegetable Grade) Generally_safe

It is used to prevent ingredients from sticking to manufacturing equipment.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Ascorbic Acid Safe

Prevents oxidation and provides vitamin C.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$23$22$21$20$19 Mar 12 $20.97
Vitacost

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Natural Factors

Founded 1950 · Coquitlam, British Columbia, Canada · 390 products · naturalfactors.com

Certifications

5 certifications
B Corp Certified Verified Source
Usp Verified Verified Source
Fda Gmp Inspections Verified Source
Non Gmo Project Verified Source
Usda Organic Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

5 incidents
Prop 65 Lead2025-10-31Source
Recall Hi Potency B Complex, RevitalX, Super Multi® IRON FREE2024-07-19Source
Lawsuit Products labeled as containing glucosamine sulfate did not contain the ingredient.2021Source
Prop 65 Lead2016-01-13Source
Recall Natural Factors L-Arginine 500mg2006-04-05Source
Related Supplements
Frequently Asked Questions
Is Natural Factors Ultimate Probiotic 12-12 Formula, 12 billion cells a good supplement?

Natural Factors Ultimate Probiotic 12-12 Formula, 12 billion cells, 60 Vegetarian Capsules received a product quality score of 84/100 in GoodSupp's independent analysis, indicating strong overall quality. The product contains 14 active ingredients with 60 servings per container. Of the 6 inactive ingredients, 2 are rated safe and 0 are flagged for review. The manufacturer, Natural Factors, holds a brand trust score of 88/100 with 5 verified certifications including B Corp Certified, Usp Verified, Fda Gmp Inspections, Non Gmo Project.

What are the ingredients in Natural Factors Ultimate Probiotic 12-12 Formula, 12 billion cells?

Natural Factors Ultimate Probiotic 12-12 Formula, 12 billion cells contains 14 active ingredients: Proprietary Synergistic Blend:, Total Active Cell Count (12 billion), Lactobacillus Casei (3 billion), Lactobacillus Rhamnosus (1.44 billion), Lactobacillus Rhamnosus (B) (1.2 billion), Lactobacillus Acidophilus (1.2 billion), and 8 more. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Natural Factors Ultimate Probiotic 12-12 Formula, 12 billion cells safe to take?

Natural Factors Ultimate Probiotic 12-12 Formula, 12 billion cells, 60 Vegetarian Capsules has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Natural Factors a trustworthy supplement brand?

Natural Factors receives a brand trust score of 88/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1950 and headquartered in Coquitlam, British Columbia, Canada, the company offers 390 products in their lineup. They hold 5 verified certifications including B Corp Certified, Usp Verified, Fda Gmp Inspections, Non Gmo Project. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Natural Factors has 5 historical regulatory incidents on record, which are factored into the trust score.

Do probiotics make you poop?

The effects of supplements on the body vary based on the specific ingredients, dosages, and individual factors. Quality clinical research is the best guide for understanding what supplements actually do versus marketing claims. Be cautious of products that promise dramatic results — legitimate supplements support health gradually, not overnight. Checking the ingredient label, understanding the dosages, and reviewing the scientific evidence are essential steps before starting any supplement. GoodSupp evaluates over 250,000 products based on published research and evidence-based criteria.

What are probiotics good for?

Probiotics Good For is a topic many supplement consumers ask about. In the context of dietary supplements, understanding probiotics good for helps you make more informed choices about what you put in your body. The quality and form of ingredients matters significantly — two products listing the same ingredient can differ dramatically in bioavailability and effectiveness. GoodSupp analyzes over 250,000 supplement products to help consumers understand exactly what's in their supplements and whether the formulation meets quality standards.

Do probiotics help with constipation?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.