Metagenics Clear Change®, 10-Day Detox Program, Vanilla, 4 Piece Set supplement bottle
Metagenics

Clear Change®, 10-Day Detox Program, Vanilla, 4 Piece Set

What We Researched
51 active ingredients analyzed · 14 inactive ingredients decoded · 7 brand certifications checked · 2 retailers compared · Last updated: Mar 2026
76
Product Score Fair
93
Brand Score Excellent

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin A (88% as beta-carotene)(as beta-carotene and retinyl palmitate) 1,350 mcg 150%
Vitamin C (as ascorbic acid) 300 mg 333%
Vitamin D (as cholecalciferol) (35 IU) 0.8 mcg 4%
Vitamin E (as d-alpha tocopheryl acetate) 28.1 mg 188%
Thiamin (as thiamin HCl) 2 mg 167%
Riboflavin 2 mg 154%
Niacin (as niacinamide) 9 mg 56%
Vitamin B6 (as pyridoxine HCl) 3.4 mg 200%
Folate (as calcium L-5-methyltetrahydrofolate) 135 mcg DFE 34%
Vitamin B12 (as methylcobalamin) 3.6 mcg 150%
Biotin 135 mcg 450%
Pantothenic Acid (as D-calcium pantothenate) 36 mg 720%
Calcium (as calcium citrate) 150 mg 13%
Iron 2 mg 11%
Phosphorus (as dipotassium phosphate) 290 mg 23%
Iodine (as potassium iodide) 53 mcg 35%
Magnesium (as magnesium citrate and magnesium sulfate) 170 mg 40%
Zinc (as Zinc gluconate) 11 mg 100%
Copper (as copper gluconate) 1 mg 111%
Manganese 0.5 mg 22%
Chromium (as chromium picolinate) 50 mcg 143%
Chloride 150 mg 7%
Potassium (as dipotassium phosphate, potassium citrate, and potassium iodide) 600 mg 13%
Glycine 1.6 g ***
L-Alanine 350 mg ***
Rice Protein Matrix and Polyphenols from Hops (Humulus lupulus L.) Cone Extract(standardized to 2.5% xanthohumol) 250 mg ***
Broccoli (Brassica oleracea L. var. italica) Sprout and Floret Powder (myrosinaseactivity 30 mg glucose/g) [providing 0.75 mg sulforaphane potential from 1.5 mgglucoraphanin] 153 mg ***
L-Lysine (as L-lysine HCl) 150 mg ***
L-Glutamine 150 mg ***
DL-Methionine 140 mg ***
N-Acetyl-L-Cysteine 125 mg ***
Prune (Prunus domestica) Skin Extract 125 mg ***
Taurine 110 mg ***
L-Tyrosine 100 mg ***
L-Arginine 70 mg ***
Ornithine (as ornithine HCl) 70 mg ***
Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract 67 mg ***
Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 72 mg gallicacid equivalent (GAE)] 137.5 mg ***
Decaffeinated‡‡Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (15 mg) catechins and 40% (10 mg) epigallocatechin gallate (EGCG)] 25 mg ***
Sulfate (as magnesium sulfate) 20 mg ***
Dried Melon (Cucumis melo L.) Pulp JuiceConcentrate [standardized to 35 IU superoxide dismutase (SOD)] 2.6 mg ***
Bioavailability Very Good

Absorption Rating

  • Vitamin A (88% as beta-carotene)(as beta-carotene and retinyl palmitate) Good
  • Vitamin C (as ascorbic acid) Fair
  • Vitamin D (as cholecalciferol) (35 IU) Good
  • Vitamin E (as d-alpha tocopheryl acetate) Good
  • Thiamin (as thiamin HCl) Fair
  • Riboflavin Good
  • Niacin (as niacinamide) Good
  • Vitamin B6 (as pyridoxine HCl) Fair
  • Folate (as calcium L-5-methyltetrahydrofolate) Good
  • Vitamin B12 (as methylcobalamin) Good
  • Biotin Good
  • Pantothenic Acid (as D-calcium pantothenate) Good
  • Calcium (as calcium citrate) Good
  • Iron Fair
  • Phosphorus (as dipotassium phosphate) Good
  • Iodine (as potassium iodide) Good
  • Magnesium (as magnesium citrate and magnesium sulfate) Good
  • Zinc (as Zinc gluconate) Good
  • Copper (as copper gluconate) Good
  • Manganese Good
  • Chromium (as chromium picolinate) Good
  • Chloride Good
  • Potassium (as dipotassium phosphate, potassium citrate, and potassium iodide) Good
  • Glycine Good
  • L-Alanine Good
  • Rice Protein Matrix and Polyphenols from Hops (Humulus lupulus L.) Cone Extract(standardized to 2.5% xanthohumol) Good
  • Broccoli (Brassica oleracea L. var. italica) Sprout and Floret Powder (myrosinaseactivity 30 mg glucose/g) [providing 0.75 mg sulforaphane potential from 1.5 mgglucoraphanin] Good
  • L-Lysine (as L-lysine HCl) Good
  • L-Glutamine Good
  • DL-Methionine Good
  • N-Acetyl-L-Cysteine Good
  • Prune (Prunus domestica) Skin Extract Good
  • Taurine Good
  • L-Tyrosine Good
  • L-Arginine Good
  • Ornithine (as ornithine HCl) Good
  • Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract Fair
  • Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 72 mg gallicacid equivalent (GAE)] Fair
  • Decaffeinated‡‡Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (15 mg) catechins and 40% (10 mg) epigallocatechin gallate (EGCG)] Fair
  • Sulfate (as magnesium sulfate) Fair
  • Dried Melon (Cucumis melo L.) Pulp JuiceConcentrate [standardized to 35 IU superoxide dismutase (SOD)] Fair
Other Ingredients Very Good

Fillers & Additives

  • Rice Protein Concentrate
  • Pea Protein Isolate
  • Bamboo Fiber
  • Gum Acacia
  • Olive Oil
  • Medium Chain Triglyceride
  • Natural Flavors
  • Silica
  • Xanthan Gum
  • Luo Han Guo Fruit Extract
  • Guar Gum
  • Rice Maltodextrin
  • Palm Oil
  • Hydrogenated Medium
Efficacy Poor

Dosage Analysis

  • Vitamin A (88% as beta-carotene)(as beta-carotene and retinyl palmitate) 1,350 mcg Effective
  • Vitamin C (as ascorbic acid) 300 mg Effective
  • Vitamin D (as cholecalciferol) (35 IU) 0.8 mcg Under-dosed
  • Vitamin E (as d-alpha tocopheryl acetate) 28.1 mg Effective
  • Thiamin (as thiamin HCl) 2 mg Effective
  • Riboflavin 2 mg Effective
  • Niacin (as niacinamide) 9 mg Under-dosed
  • Vitamin B6 (as pyridoxine HCl) 3.4 mg Effective
  • Folate (as calcium L-5-methyltetrahydrofolate) 135 mcg DFE Under-dosed
  • Vitamin B12 (as methylcobalamin) 3.6 mcg Effective
  • Biotin 135 mcg Effective
  • Pantothenic Acid (as D-calcium pantothenate) 36 mg Effective
  • Calcium (as calcium citrate) 150 mg Under-dosed
  • Iron 2 mg Under-dosed
  • Phosphorus (as dipotassium phosphate) 290 mg Under-dosed
  • Iodine (as potassium iodide) 53 mcg Under-dosed
  • Magnesium (as magnesium citrate and magnesium sulfate) 170 mg Under-dosed
  • Zinc (as Zinc gluconate) 11 mg Effective
  • Copper (as copper gluconate) 1 mg Effective
  • Manganese 0.5 mg Under-dosed
  • Chromium (as chromium picolinate) 50 mcg Effective
  • Chloride 150 mg Under-dosed
  • Potassium (as dipotassium phosphate, potassium citrate, and potassium iodide) 600 mg Under-dosed
  • Glycine 1.6 g Under-dosed
  • L-Lysine (as L-lysine HCl) 150 mg Under-dosed
  • L-Glutamine 150 mg Under-dosed
  • DL-Methionine 140 mg Under-dosed
  • N-Acetyl-L-Cysteine 125 mg Under-dosed
  • Prune (Prunus domestica) Skin Extract 125 mg Under-dosed
  • Taurine 110 mg Under-dosed
  • L-Tyrosine 100 mg Under-dosed
  • L-Arginine 70 mg Under-dosed
  • Ornithine (as ornithine HCl) 70 mg Under-dosed
  • Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract 67 mg Under-dosed
  • Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 72 mg gallicacid equivalent (GAE)] 137.5 mg Under-dosed
  • Decaffeinated‡‡Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (15 mg) catechins and 40% (10 mg) epigallocatechin gallate (EGCG)] 25 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Calories 90
Total Fat 3 g 4%**
Saturated Fat 1 g 5%**
Polyunsaturated Fat 1 g
Monounsaturated Fat 1 g
Total Carbohydrate 12 g 4%**
Dietary Fiber 7 g 25%**
Total Sugars 1 g
Protein 12 g 19%**
Vitamin A (88% as beta-carotene)(as beta-carotene and retinyl palmitate) 1,350 mcg 150%
Vitamin C (as ascorbic acid) 300 mg 333%
Vitamin D (as cholecalciferol) (35 IU) 0.8 mcg 4%
Vitamin E (as d-alpha tocopheryl acetate) 28.1 mg 188%
Thiamin (as thiamin HCl) 2 mg 167%
Riboflavin 2 mg 154%
Niacin (as niacinamide) 9 mg 56%
Vitamin B6 (as pyridoxine HCl) 3.4 mg 200%
Folate (as calcium L-5-methyltetrahydrofolate) 135 mcg DFE 34%
Vitamin B12 (as methylcobalamin) 3.6 mcg 150%
Biotin 135 mcg 450%
Pantothenic Acid (as D-calcium pantothenate) 36 mg 720%
Calcium (as calcium citrate) 150 mg 13%
Iron 2 mg 11%
Phosphorus (as dipotassium phosphate) 290 mg 23%
Iodine (as potassium iodide) 53 mcg 35%
Magnesium (as magnesium citrate and magnesium sulfate) 170 mg 40%
Zinc (as Zinc gluconate) 11 mg 100%
Copper (as copper gluconate) 1 mg 111%
Manganese 0.5 mg 22%
Chromium (as chromium picolinate) 50 mcg 143%
Chloride 150 mg 7%
Sodium 80 mg 3%
Potassium (as dipotassium phosphate, potassium citrate, and potassium iodide) 600 mg 13%
Glycine 1.6 g ***
L-Alanine 350 mg ***
Rice Protein Matrix and Polyphenols from Hops (Humulus lupulus L.) Cone Extract(standardized to 2.5% xanthohumol) 250 mg ***
Broccoli (Brassica oleracea L. var. italica) Sprout and Floret Powder (myrosinaseactivity 30 mg glucose/g) [providing 0.75 mg sulforaphane potential from 1.5 mgglucoraphanin] 153 mg ***
L-Lysine (as L-lysine HCl) 150 mg ***
L-Glutamine 150 mg ***
DL-Methionine 140 mg ***
N-Acetyl-L-Cysteine 125 mg ***
Prune (Prunus domestica) Skin Extract 125 mg ***
Taurine 110 mg ***
L-Tyrosine 100 mg ***
L-Arginine 70 mg ***
Ornithine (as ornithine HCl) 70 mg ***
Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract 67 mg ***
Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 72 mg gallicacid equivalent (GAE)] 137.5 mg ***
Decaffeinated‡‡Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (15 mg) catechins and 40% (10 mg) epigallocatechin gallate (EGCG)] 25 mg ***
Sulfate (as magnesium sulfate) 20 mg ***
Dried Melon (Cucumis melo L.) Pulp JuiceConcentrate [standardized to 35 IU superoxide dismutase (SOD)] 2.6 mg ***

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Rice Protein Concentrate Generally_safe

It is used as a filler or protein source.

Pea Protein Isolate Safe

It is used as a protein source and filler.

Bamboo Fiber Unknown
Gum Acacia Safe

It is used as a thickener, binder, or emulsifier.

Olive Oil Safe

Helps dissolve and absorb fat-soluble vitamins (A, D, E, K).

Medium Chain Triglyceride Unknown
Natural Flavors Safe

Improves taste of chewable, gummy, or liquid supplements.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Xanthan Gum Safe

Thickens and stabilizes liquid and semi-solid supplements.

Luo Han Guo Fruit Extract Unknown
Guar Gum Safe

Thickens and provides fiber in supplement formulations.

Rice Maltodextrin Generally_safe

It is used as a filler or binder.

Palm Oil Generally_safe

Used as a carrier for fat-soluble ingredients.

Hydrogenated Unknown

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$93$92$91$90$89 Mar 12 $91.00
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Metagenics

Founded 1983 · Aliso Viejo, California, United States · 185 products · metagenics.com

Certifications

7 certifications
B Corp Certified Verified Source
Consumerlab Verified
Gluten Free Gfco Verified Source
Non Gmo Project Verified Source
Fda Gmp Inspections Verified Source
Nsf Gmp Verified Source
Usp Verified Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Coa Availability — Claimed Source
In House Testing — Verified Source

Violation History

3 incidents
Fda Warning A structure/function claim for 'Metagenics HerWellness Naturally Balanced' was deemed by the FDA to suggest the product is intended for use as a drug.2025-02-07Source
Prop 65 Lead2019-05-30Source
Fda Warning Mislabeling of 14 products as medical foods and making unapproved new drug claims.2013-08-13Source
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Frequently Asked Questions
Is Metagenics Clear Change®, 10-Day Detox Program a good supplement?

Metagenics Clear Change®, 10-Day Detox Program, Vanilla, 4 Piece Set received a product quality score of 76/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 51 active ingredients with 21 servings per container. Of the 14 inactive ingredients, 7 are rated safe and 0 are flagged for review. The manufacturer, Metagenics, holds a brand trust score of 93/100 with 7 verified certifications including B Corp Certified, Consumerlab, Gluten Free Gfco, Non Gmo Project.

What are the ingredients in Metagenics Clear Change®, 10-Day Detox Program?

Metagenics Clear Change®, 10-Day Detox Program contains 51 active ingredients: Calories (90), Total Fat (3 g), Saturated Fat (1 g), Polyunsaturated Fat (1 g), Monounsaturated Fat (1 g), Total Carbohydrate (12 g), and 45 more. Notable high-dose ingredients include Vitamin C at 333% DV, Biotin at 450% DV, Pantothenic Acid at 720% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Metagenics Clear Change®, 10-Day Detox Program safe to take?

Metagenics Clear Change®, 10-Day Detox Program, Vanilla, 4 Piece Set has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Metagenics a trustworthy supplement brand?

Metagenics receives a brand trust score of 93/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1983 and headquartered in Aliso Viejo, California, United States, the company offers 185 products in their lineup. They hold 7 verified certifications including B Corp Certified, Consumerlab, Gluten Free Gfco, Non Gmo Project. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Metagenics has 3 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.