Metagenics Axis Endo™, Mango, 1 lb 3.26 oz (546 g) supplement bottle
Metagenics

Axis Endo™, Mango, 1 lb 3.26 oz (546 g)

What We Researched
39 active ingredients analyzed · 12 inactive ingredients decoded · 7 brand certifications checked · 2 retailers compared · Last updated: Mar 2026
79
Product Score Fair
93
Brand Score Excellent

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin A (from mixed carotenoids) 750 mcg 83%
Vitamin C (as ascorbic acid) 60 mg 67%
Vitamin D (as cholecalciferol) (1,000 IU) 25 mcg 125%
Vitamin E (as d-alpha tocopheryl succinate) 201 mg 1,340%
Vitamin K (as phylloquinone) 75 mcg 63%
Thiamin (as thiamin HCl) 0.75 mg 63%
Riboflavin 1 mg 77%
Niacin (as niacinamide) 12 mg 75%
Vitamin B6 (as pyridoxine HCl) 50 mg 2,941%
Folate (as calcium L-5-methyltetrahydrofolate)† 680 mcg DFE 170%
Vitamin B12 (as methylcobalamin) 300 mcg 12,500%
Biotin 150 mcg 500%
Pantothenic Acid (as calcium D-pantothenate) 5 mg 100%
Calcium (as calcium D-glucarate and calcium citrate) 500 mg 38%
Iron (as ferrous fumarate) 8 mg 44%
Phosphorous 350 mg 28%
Iodine (as potassium iodide) 100 mcg 67%
Magnesium (as magnesium citrate) 200 mg 48%
Zinc (as zinc citrate) 12 mg 109%
Manganese (as manganese sulfate) 1 mg 43%
Chromium (as chromium picolinate) 100 mcg 286%
Potassium (as dipotassium phosphate) 400 mg 9%
Calcium D-Glucarate 1.5 g ***
Milk Thistle (Silybum marianum) Seed Extract providing 140 mg silymarin††(containing silybin, isosilybin, silydianin, silychristin) 280 mg ***
Proprietary Mix of Curcumin[from Curcuma longa L rhizome extract standardized to 40% (40 mg) curcuminoids] and Fenugreek Galactomannans (from Trigonella foenum-graecum seed extract) 100 mg **
N-Acetyl-L-Cysteine 100 mg **
Rosemary (Rosmarinus officinalis) Leaf Extract (standardized to 7.6% min sum of carnosol+carnosic acid) 100 mg ***
Secoisolariciresinol Diglucoside (SDG) (from flaxseed lignans) 95 mg ***
Dried Melon (Cucumis melo L.) Pulp Juice Concentrate [standardized to 140 IU superoxide dismutase (SOD)] 10 mg ***
Mixed Carotenoids(including beta-carotene, alpha-carotene, cryptoxanthin, zeaxanthin, and lutein) 1.5 mg ***
Menaquinone-7 (MK-7) 15 mcg ***
Bioavailability Very Good

Absorption Rating

  • Vitamin A (from mixed carotenoids) Good
  • Vitamin C (as ascorbic acid) Fair
  • Vitamin D (as cholecalciferol) (1,000 IU) Good
  • Vitamin E (as d-alpha tocopheryl succinate) Good
  • Vitamin K (as phylloquinone) Fair
  • Thiamin (as thiamin HCl) Fair
  • Riboflavin Good
  • Niacin (as niacinamide) Good
  • Vitamin B6 (as pyridoxine HCl) Fair
  • Folate (as calcium L-5-methyltetrahydrofolate)† Good
  • Vitamin B12 (as methylcobalamin) Good
  • Biotin Good
  • Pantothenic Acid (as calcium D-pantothenate) Good
  • Calcium (as calcium D-glucarate and calcium citrate) Good
  • Iron (as ferrous fumarate) Fair
  • Phosphorous Fair
  • Iodine (as potassium iodide) Good
  • Magnesium (as magnesium citrate) Good
  • Zinc (as zinc citrate) Good
  • Manganese (as manganese sulfate) Good
  • Chromium (as chromium picolinate) Good
  • Potassium (as dipotassium phosphate) Good
  • Calcium D-Glucarate Good
  • Milk Thistle (Silybum marianum) Seed Extract providing 140 mg silymarin††(containing silybin, isosilybin, silydianin, silychristin) Poor
  • Proprietary Mix of Curcumin[from Curcuma longa L rhizome extract standardized to 40% (40 mg) curcuminoids] and Fenugreek Galactomannans (from Trigonella foenum-graecum seed extract) Poor
  • N-Acetyl-L-Cysteine Good
  • Rosemary (Rosmarinus officinalis) Leaf Extract (standardized to 7.6% min sum of carnosol+carnosic acid) Fair
  • Secoisolariciresinol Diglucoside (SDG) (from flaxseed lignans) Fair
  • Dried Melon (Cucumis melo L.) Pulp Juice Concentrate [standardized to 140 IU superoxide dismutase (SOD)] Fair
  • Mixed Carotenoids(including beta-carotene, alpha-carotene, cryptoxanthin, zeaxanthin, and lutein) Good
  • Menaquinone-7 (MK-7) Good
Other Ingredients Very Good

Fillers & Additives

  • Pea Protein Isolate
  • Rice Protein Concentrate
  • Apple Fiber
  • Partially Hydrolyzed Guar Gum
  • Olive Oil
  • Medium-Chain Triglycerides
  • Natural flavors^
  • Tapioca flour
  • Silica
  • Mono and Diglycerides
  • Luo Han Guo Fruit (Monk Fruit) Extract
  • Hydrogenated palm oil Medium
Efficacy Fair

Dosage Analysis

  • Vitamin A (from mixed carotenoids) 750 mcg Effective
  • Vitamin C (as ascorbic acid) 60 mg Under-dosed
  • Vitamin D (as cholecalciferol) (1,000 IU) 25 mcg Effective
  • Vitamin E (as d-alpha tocopheryl succinate) 201 mg High
  • Vitamin K (as phylloquinone) 75 mcg Under-dosed
  • Thiamin (as thiamin HCl) 0.75 mg Under-dosed
  • Riboflavin 1 mg Effective
  • Niacin (as niacinamide) 12 mg Under-dosed
  • Vitamin B6 (as pyridoxine HCl) 50 mg Effective
  • Folate (as calcium L-5-methyltetrahydrofolate)† 680 mcg DFE Effective
  • Vitamin B12 (as methylcobalamin) 300 mcg Effective
  • Biotin 150 mcg Effective
  • Pantothenic Acid (as calcium D-pantothenate) 5 mg Effective
  • Calcium (as calcium D-glucarate and calcium citrate) 500 mg Effective
  • Iron (as ferrous fumarate) 8 mg Effective
  • Iodine (as potassium iodide) 100 mcg Under-dosed
  • Magnesium (as magnesium citrate) 200 mg Effective
  • Zinc (as zinc citrate) 12 mg Effective
  • Manganese (as manganese sulfate) 1 mg Under-dosed
  • Chromium (as chromium picolinate) 100 mcg Effective
  • Potassium (as dipotassium phosphate) 400 mg Under-dosed
  • Calcium D-Glucarate 1.5 g High
  • Milk Thistle (Silybum marianum) Seed Extract providing 140 mg silymarin††(containing silybin, isosilybin, silydianin, silychristin) 280 mg Effective
  • Proprietary Mix of Curcumin[from Curcuma longa L rhizome extract standardized to 40% (40 mg) curcuminoids] and Fenugreek Galactomannans (from Trigonella foenum-graecum seed extract) 100 mg Under-dosed
  • N-Acetyl-L-Cysteine 100 mg Under-dosed
  • Secoisolariciresinol Diglucoside (SDG) (from flaxseed lignans) 95 mg Effective
  • Mixed Carotenoids(including beta-carotene, alpha-carotene, cryptoxanthin, zeaxanthin, and lutein) 1.5 mg Under-dosed
  • Menaquinone-7 (MK-7) 15 mcg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Calories 120
Total Fat 4 g 5%**
Total Carbohydrate 11 g 4%**
Dietary Fiber 7 g 25%**
Total Sugars 3 g
Includes 1 g Added Sugars 1%**
Protein 13 g
Vitamin A (from mixed carotenoids) 750 mcg 83%
Vitamin C (as ascorbic acid) 60 mg 67%
Vitamin D (as cholecalciferol) (1,000 IU) 25 mcg 125%
Vitamin E (as d-alpha tocopheryl succinate) 201 mg 1,340%
Vitamin K (as phylloquinone) 75 mcg 63%
Thiamin (as thiamin HCl) 0.75 mg 63%
Riboflavin 1 mg 77%
Niacin (as niacinamide) 12 mg 75%
Vitamin B6 (as pyridoxine HCl) 50 mg 2,941%
Folate (as calcium L-5-methyltetrahydrofolate)† 680 mcg DFE 170%
Vitamin B12 (as methylcobalamin) 300 mcg 12,500%
Biotin 150 mcg 500%
Pantothenic Acid (as calcium D-pantothenate) 5 mg 100%
Calcium (as calcium D-glucarate and calcium citrate) 500 mg 38%
Iron (as ferrous fumarate) 8 mg 44%
Phosphorous 350 mg 28%
Iodine (as potassium iodide) 100 mcg 67%
Magnesium (as magnesium citrate) 200 mg 48%
Zinc (as zinc citrate) 12 mg 109%
Manganese (as manganese sulfate) 1 mg 43%
Chromium (as chromium picolinate) 100 mcg 286%
Sodium 120 mg 5%
Potassium (as dipotassium phosphate) 400 mg 9%
Calcium D-Glucarate 1.5 g ***
Milk Thistle (Silybum marianum) Seed Extract providing 140 mg silymarin††(containing silybin, isosilybin, silydianin, silychristin) 280 mg ***
Proprietary Mix of Curcumin[from Curcuma longa L rhizome extract standardized to 40% (40 mg) curcuminoids] and Fenugreek Galactomannans (from Trigonella foenum-graecum seed extract) 100 mg **
N-Acetyl-L-Cysteine 100 mg **
Rosemary (Rosmarinus officinalis) Leaf Extract (standardized to 7.6% min sum of carnosol+carnosic acid) 100 mg ***
Secoisolariciresinol Diglucoside (SDG) (from flaxseed lignans) 95 mg ***
Dried Melon (Cucumis melo L.) Pulp Juice Concentrate [standardized to 140 IU superoxide dismutase (SOD)] 10 mg ***
Mixed Carotenoids(including beta-carotene, alpha-carotene, cryptoxanthin, zeaxanthin, and lutein) 1.5 mg ***
Menaquinone-7 (MK-7) 15 mcg ***

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Pea Protein Isolate Safe

It is used as a protein source and filler.

Rice Protein Concentrate Generally_safe

It is used as a filler or protein source.

Apple Fiber Safe

It is used to add bulk and improve the texture of supplements.

Partially Hydrolyzed Guar Gum Generally_safe

It is used as a thickener, stabilizer, or source of fiber.

Olive Oil Safe

Helps dissolve and absorb fat-soluble vitamins (A, D, E, K).

Medium-Chain Triglycerides Generally_safe
Natural flavors^ Unknown
Tapioca flour Unknown
Silica Safe

Prevents ingredients from clumping and improves powder flow.

Mono and Diglycerides Generally_safe

They are used to help mix oil and water-based ingredients.

Luo Han Guo Fruit (Monk Fruit) Extract Generally_safe

It is used as a natural, low-calorie sweetener in supplements.

Hydrogenated palm oil Unknown

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$89$88$87$86$85 Mar 12 $87.45
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Metagenics

Founded 1983 · Aliso Viejo, California, United States · 185 products · metagenics.com

Certifications

7 certifications
B Corp Certified Verified Source
Consumerlab Verified
Gluten Free Gfco Verified Source
Non Gmo Project Verified Source
Fda Gmp Inspections Verified Source
Nsf Gmp Verified Source
Usp Verified Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Coa Availability — Claimed Source
In House Testing — Verified Source

Violation History

3 incidents
Fda Warning A structure/function claim for 'Metagenics HerWellness Naturally Balanced' was deemed by the FDA to suggest the product is intended for use as a drug.2025-02-07Source
Prop 65 Lead2019-05-30Source
Fda Warning Mislabeling of 14 products as medical foods and making unapproved new drug claims.2013-08-13Source
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Frequently Asked Questions
Is Metagenics Axis Endo™, Mango a good supplement?

Metagenics Axis Endo™, Mango, 1 lb 3.26 oz (546 g) received a product quality score of 79/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 39 active ingredients with 14 servings per container. Of the 12 inactive ingredients, 4 are rated safe and 0 are flagged for review. The manufacturer, Metagenics, holds a brand trust score of 93/100 with 7 verified certifications including B Corp Certified, Consumerlab, Gluten Free Gfco, Non Gmo Project.

What are the ingredients in Metagenics Axis Endo™, Mango?

Metagenics Axis Endo™, Mango contains 39 active ingredients: Calories (120), Total Fat (4 g), Total Carbohydrate (11 g), Dietary Fiber (7 g), Total Sugars (3 g), Includes 1 g Added Sugars, and 33 more. Notable high-dose ingredients include Vitamin E at 1,340% DV, Vitamin B6 at 2,941% DV, Vitamin B12 at 12,500% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Metagenics Axis Endo™, Mango safe to take?

Metagenics Axis Endo™, Mango, 1 lb 3.26 oz (546 g) has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Metagenics a trustworthy supplement brand?

Metagenics receives a brand trust score of 93/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1983 and headquartered in Aliso Viejo, California, United States, the company offers 185 products in their lineup. They hold 7 verified certifications including B Corp Certified, Consumerlab, Gluten Free Gfco, Non Gmo Project. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Metagenics has 3 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.