Metagenics AdvaClear®, Detox, 126 Capsules supplement bottle
Metagenics

AdvaClear®, Detox, 126 Capsules

What We Researched
26 active ingredients analyzed · 4 inactive ingredients decoded · 7 brand certifications checked · 2 retailers compared · Last updated: Mar 2026
83
Product Score Good
93
Brand Score Excellent

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin A (from mixed carotenoids†† and retinyl palmitate) 750 mcg 83%
Vitamin C (as ascorbic acid) 133 mg 148%
Vitamin D (as cholecalciferol) (33 IU) 0.8 mcg 4%
Vitamin E (as d-alpha tocopheryl succinate) 44.6 mg 297%
Thiamin (as thiamin mononitrate) 10 mg 833%
Riboflavin 5 mg 385%
Niacin (as niacinamide and niacin) 23.3 mg 146%
Vitamin B6 (as pyridoxine HCl) 16.66 mg 980%
Folate (as calcium L-5-methyltetrahydrofolate) 445 mcg DFE 111%
Vitamin B12 (as methylcobalamin) 33.4 mcg 1,392%
Biotin 66 mcg 220%
Pantothenic Acid (as calcium D-pantothenate) 33.3 mg 666%
Zinc (as zinc citrate) 6.5 mg 59%
Selenium (as selenomethionine) 50 mcg 91%
Copper (as copper citrate) 0.66 mg 73%
Manganese (as manganese citrate) 1.66 mg 72%
Molybdenum (as molybdenum aspartate complex) 66 mcg 147%
Sodium (as sodium sulfate) 40 mg 2%
Artichoke (Cynara scolymus) Leaf Extract (containing cynarin and chlorogenic acid) 167 mg *
Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract 133 mg *
Taurine 117 mg *
Sodium Sulfate 100 mg *
Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 45.8 mg gallic acid equivalent (GAE)] 87.5 mg *
N-Acetyl-L-Cysteine 67 mg *
Decaffeinated‡ Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (33.6 mg) catechins and 40% (22.4 mg) epigallocatechin gallate (EGCG)] 56 mg *
Silymarin [from milk thistle (Silybum marianum) seed extract] 50 mg *
Bioavailability Very Good

Absorption Rating

  • Vitamin A (from mixed carotenoids†† and retinyl palmitate) Good
  • Vitamin C (as ascorbic acid) Fair
  • Vitamin D (as cholecalciferol) (33 IU) Good
  • Vitamin E (as d-alpha tocopheryl succinate) Good
  • Thiamin (as thiamin mononitrate) Fair
  • Riboflavin Good
  • Niacin (as niacinamide and niacin) Good
  • Vitamin B6 (as pyridoxine HCl) Fair
  • Folate (as calcium L-5-methyltetrahydrofolate) Good
  • Vitamin B12 (as methylcobalamin) Good
  • Biotin Good
  • Pantothenic Acid (as calcium D-pantothenate) Good
  • Zinc (as zinc citrate) Good
  • Selenium (as selenomethionine) Good
  • Copper (as copper citrate) Good
  • Manganese (as manganese citrate) Good
  • Molybdenum (as molybdenum aspartate complex) Good
  • Sodium (as sodium sulfate) Good
  • Artichoke (Cynara scolymus) Leaf Extract (containing cynarin and chlorogenic acid) Fair
  • Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract Fair
  • Taurine Good
  • Sodium Sulfate Fair
  • Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 45.8 mg gallic acid equivalent (GAE)] Fair
  • N-Acetyl-L-Cysteine Good
  • Decaffeinated‡ Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (33.6 mg) catechins and 40% (22.4 mg) epigallocatechin gallate (EGCG)] Fair
  • Silymarin [from milk thistle (Silybum marianum) seed extract] Poor
Other Ingredients Excellent

Fillers & Additives

  • Hydroxypropyl Methylcellulose
  • Microcrystalline Cellulose
  • Magnesium Stearate
  • Silica
Efficacy Fair

Dosage Analysis

  • Vitamin A (from mixed carotenoids†† and retinyl palmitate) 750 mcg Effective
  • Vitamin C (as ascorbic acid) 133 mg Effective
  • Vitamin D (as cholecalciferol) (33 IU) 0.8 mcg Under-dosed
  • Vitamin E (as d-alpha tocopheryl succinate) 44.6 mg Effective
  • Thiamin (as thiamin mononitrate) 10 mg Effective
  • Riboflavin 5 mg Effective
  • Niacin (as niacinamide and niacin) 23.3 mg Effective
  • Vitamin B6 (as pyridoxine HCl) 16.66 mg Effective
  • Folate (as calcium L-5-methyltetrahydrofolate) 445 mcg DFE Effective
  • Vitamin B12 (as methylcobalamin) 33.4 mcg Effective
  • Biotin 66 mcg Effective
  • Pantothenic Acid (as calcium D-pantothenate) 33.3 mg Effective
  • Zinc (as zinc citrate) 6.5 mg Under-dosed
  • Selenium (as selenomethionine) 50 mcg Effective
  • Copper (as copper citrate) 0.66 mg Effective
  • Manganese (as manganese citrate) 1.66 mg Under-dosed
  • Molybdenum (as molybdenum aspartate complex) 66 mcg Effective
  • Sodium (as sodium sulfate) 40 mg Under-dosed
  • Artichoke (Cynara scolymus) Leaf Extract (containing cynarin and chlorogenic acid) 167 mg Under-dosed
  • Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract 133 mg Under-dosed
  • Taurine 117 mg Under-dosed
  • Sodium Sulfate 100 mg Under-dosed
  • Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 45.8 mg gallic acid equivalent (GAE)] 87.5 mg Under-dosed
  • N-Acetyl-L-Cysteine 67 mg Under-dosed
  • Decaffeinated‡ Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (33.6 mg) catechins and 40% (22.4 mg) epigallocatechin gallate (EGCG)] 56 mg Under-dosed
  • Silymarin [from milk thistle (Silybum marianum) seed extract] 50 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Vitamin A (from mixed carotenoids†† and retinyl palmitate) 750 mcg 83%
Vitamin C (as ascorbic acid) 133 mg 148%
Vitamin D (as cholecalciferol) (33 IU) 0.8 mcg 4%
Vitamin E (as d-alpha tocopheryl succinate) 44.6 mg 297%
Thiamin (as thiamin mononitrate) 10 mg 833%
Riboflavin 5 mg 385%
Niacin (as niacinamide and niacin) 23.3 mg 146%
Vitamin B6 (as pyridoxine HCl) 16.66 mg 980%
Folate (as calcium L-5-methyltetrahydrofolate) 445 mcg DFE 111%
Vitamin B12 (as methylcobalamin) 33.4 mcg 1,392%
Biotin 66 mcg 220%
Pantothenic Acid (as calcium D-pantothenate) 33.3 mg 666%
Zinc (as zinc citrate) 6.5 mg 59%
Selenium (as selenomethionine) 50 mcg 91%
Copper (as copper citrate) 0.66 mg 73%
Manganese (as manganese citrate) 1.66 mg 72%
Molybdenum (as molybdenum aspartate complex) 66 mcg 147%
Sodium (as sodium sulfate) 40 mg 2%
Artichoke (Cynara scolymus) Leaf Extract (containing cynarin and chlorogenic acid) 167 mg *
Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract 133 mg *
Taurine 117 mg *
Sodium Sulfate 100 mg *
Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 45.8 mg gallic acid equivalent (GAE)] 87.5 mg *
N-Acetyl-L-Cysteine 67 mg *
Decaffeinated‡ Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (33.6 mg) catechins and 40% (22.4 mg) epigallocatechin gallate (EGCG)] 56 mg *
Silymarin [from milk thistle (Silybum marianum) seed extract] 50 mg *

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Hydroxypropyl Methylcellulose Safe

It is used as a coating for tablets and capsules.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Silica Safe

Prevents ingredients from clumping and improves powder flow.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$92$91$90$89$88 Mar 12 $90.00
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Metagenics

Founded 1983 · Aliso Viejo, California, United States · 185 products · metagenics.com

Certifications

7 certifications
B Corp Certified Verified Source
Consumerlab Verified
Gluten Free Gfco Verified Source
Non Gmo Project Verified Source
Fda Gmp Inspections Verified Source
Nsf Gmp Verified Source
Usp Verified Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Coa Availability — Claimed Source
In House Testing — Verified Source

Violation History

3 incidents
Fda Warning A structure/function claim for 'Metagenics HerWellness Naturally Balanced' was deemed by the FDA to suggest the product is intended for use as a drug.2025-02-07Source
Prop 65 Lead2019-05-30Source
Fda Warning Mislabeling of 14 products as medical foods and making unapproved new drug claims.2013-08-13Source
Related Supplements
Frequently Asked Questions
Is Metagenics AdvaClear®, Detox a good supplement?

Metagenics AdvaClear®, Detox, 126 Capsules received a product quality score of 83/100 in GoodSupp's independent analysis, indicating strong overall quality. The product contains 26 active ingredients with 63 servings per container. All 4 inactive ingredients (fillers, binders, capsule materials) are rated safe — a clean formulation with no flagged additives. The manufacturer, Metagenics, holds a brand trust score of 93/100 with 7 verified certifications including B Corp Certified, Consumerlab, Gluten Free Gfco, Non Gmo Project.

What are the ingredients in Metagenics AdvaClear®, Detox?

Metagenics AdvaClear®, Detox contains 26 active ingredients: Vitamin A (from mixed carotenoids†† and retinyl palmitate) (750 mcg), Vitamin C (as ascorbic acid) (133 mg), Vitamin D (as cholecalciferol) (33 IU) (0.8 mcg), Vitamin E (as d-alpha tocopheryl succinate) (44.6 mg), Thiamin (as thiamin mononitrate) (10 mg), Riboflavin (5 mg), and 20 more. Notable high-dose ingredients include Vitamin E at 297% DV, Thiamin at 833% DV, Riboflavin at 385% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Metagenics AdvaClear®, Detox safe to take?

Metagenics AdvaClear®, Detox, 126 Capsules has been analyzed for ingredient safety across all its components. All 4 inactive ingredients — including capsule materials, fillers, and binders — are rated safe based on regulatory data and published safety research. This is a clean formulation with no controversial additives. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Metagenics a trustworthy supplement brand?

Metagenics receives a brand trust score of 93/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1983 and headquartered in Aliso Viejo, California, United States, the company offers 185 products in their lineup. They hold 7 verified certifications including B Corp Certified, Consumerlab, Gluten Free Gfco, Non Gmo Project. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Metagenics has 3 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.