Metabolic Maintenance SAMe + Cofactors, 60 Vegetarian Capsules supplement bottle
Metabolic Maintenance

SAMe + Cofactors, 60 Vegetarian Capsules

What We Researched
6 active ingredients analyzed · 4 inactive ingredients decoded · 2 retailers compared · Last updated: Mar 2026
81
Product Score Good
68
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin B-6 (as Pyridoxal 5' Phosphate) 4 mg 236%
Folate (400 mcg from L-5-Methylfolate, calcium salt) 666 mcg DFE 163%
Vitamin B12 (as Methylcobalamin) 1000 mcg 41666%
Calcium (as Calcium Carbonate) 54 mg 4%
Magnesium (as Magnesium Citrate) 20 mg 4%
SAMe (from 888 mg S-Adenosyl-L-Methionine Disulfate p-Toluensulfonate, calcium chloride, calcium oxide) 400 mg
Bioavailability Very Good

Absorption Rating

  • Vitamin B-6 (as Pyridoxal 5' Phosphate) Fair
  • Folate (400 mcg from L-5-Methylfolate, calcium salt) Good
  • Vitamin B12 (as Methylcobalamin) Good
  • Calcium (as Calcium Carbonate) Fair
  • Magnesium (as Magnesium Citrate) Good
  • SAMe (from 888 mg S-Adenosyl-L-Methionine Disulfate p-Toluensulfonate, calcium chloride, calcium oxide) Fair
Other Ingredients Excellent

Fillers & Additives

  • Hydroxypropyl Methylcellulose
  • Microcrystalline Cellulose
  • L-Leucine
  • Silicon Dioxide
Efficacy Fair

Dosage Analysis

  • Vitamin B-6 (as Pyridoxal 5' Phosphate) 4 mg Effective
  • Folate (400 mcg from L-5-Methylfolate, calcium salt) 666 mcg DFE Effective
  • Vitamin B12 (as Methylcobalamin) 1000 mcg Effective
  • Calcium (as Calcium Carbonate) 54 mg Under-dosed
  • Magnesium (as Magnesium Citrate) 20 mg Under-dosed
  • SAMe (from 888 mg S-Adenosyl-L-Methionine Disulfate p-Toluensulfonate, calcium chloride, calcium oxide) 400 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Vitamin B-6 (as Pyridoxal 5' Phosphate) 4 mg 236%
Folate (400 mcg from L-5-Methylfolate, calcium salt) 666 mcg DFE 163%
Vitamin B12 (as Methylcobalamin) 1000 mcg 41666%
Calcium (as Calcium Carbonate) 54 mg 4%
Magnesium (as Magnesium Citrate) 20 mg 4%
SAMe (from 888 mg S-Adenosyl-L-Methionine Disulfate p-Toluensulfonate, calcium chloride, calcium oxide) 400 mg

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Hydroxypropyl Methylcellulose Safe

It is used as a coating for tablets and capsules.

Microcrystalline Cellulose Safe

Adds bulk to small-dose supplements to make tablets/capsules a manageable size.

L-Leucine Safe

It is included for its potential muscle-building and recovery benefits.

Silicon Dioxide Safe

Prevents clumping and ensures consistent dosing.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$54$53$52$51$50 Mar 12 $52.00
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Metabolic Maintenance

Founded 1984 · Sisters, Oregon, United States · 67 products · allergyresearchgroup.com/metabolic-maintenance

Transparency

3 claims
Third Party Testing Claim — Verified Source
Testing Lab Disclosure — Claimed Source

Violation History

2 incidents
Prop 65 Lead2011-07-19Source
Lawsuit Failure to provide clear and reasonable warnings about exposure to lead in various supplement products.2011Source
Related Supplements
Frequently Asked Questions
Is Metabolic Maintenance SAMe + Cofactors, 60 Vegetarian Capsules a good supplement?

Metabolic Maintenance SAMe + Cofactors, 60 Vegetarian Capsules received a product quality score of 81/100 in GoodSupp's independent analysis, indicating strong overall quality. The product contains 6 active ingredients with 30 servings per container. All 4 inactive ingredients (fillers, binders, capsule materials) are rated safe — a clean formulation with no flagged additives. The manufacturer, Metabolic Maintenance, holds a brand trust score of 68/100.

What are the ingredients in Metabolic Maintenance SAMe + Cofactors, 60 Vegetarian Capsules?

Metabolic Maintenance SAMe + Cofactors, 60 Vegetarian Capsules contains 6 active ingredients: Vitamin B-6 (as Pyridoxal 5' Phosphate) (4 mg), Folate (400 mcg from L-5-Methylfolate, calcium salt) (666 mcg DFE), Vitamin B12 (as Methylcobalamin) (1000 mcg), Calcium (as Calcium Carbonate) (54 mg), Magnesium (as Magnesium Citrate) (20 mg), SAMe (from 888 mg S-Adenosyl-L-Methionine Disulfate p-Toluensulfonate, calcium chloride, calcium oxide) (400 mg). Notable high-dose ingredients include Vitamin B-6 at 236% DV, Vitamin B12 at 41666% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Metabolic Maintenance SAMe + Cofactors, 60 Vegetarian Capsules safe to take?

Metabolic Maintenance SAMe + Cofactors, 60 Vegetarian Capsules has been analyzed for ingredient safety across all its components. All 4 inactive ingredients — including capsule materials, fillers, and binders — are rated safe based on regulatory data and published safety research. This is a clean formulation with no controversial additives. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Metabolic Maintenance a trustworthy supplement brand?

Metabolic Maintenance receives a brand trust score of 68/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1984 and headquartered in Sisters, Oregon, United States, the company offers 67 products in their lineup. Note: Metabolic Maintenance has 2 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.