Irwin Naturals Double Potency 5-HTP Extra™, 60 Liquid Softgels supplement bottle
Irwin Naturals

Double Potency 5-HTP Extra™, 60 Liquid Softgels

What We Researched
12 active ingredients analyzed · 10 inactive ingredients decoded · 1 brand certification checked · 3 retailers compared · Last updated: Mar 2026
64
Product Score Fair
78
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin D (as Cholecalciferol) 500 IU 125%
Vitamin B6 (as Pyridoxine Hydrochloride) 10 mg 500%
Magnesium (as Magnesium Citrate) 50 mg 12%
Fish Oil (18% EPA/12% DHA) 600 mg *
5-HTP (Griffonia simplicifolia) (seed) 100 mg *
Lemon Balm extract (4:1) (aerial) 100 mg *
Rhodiola extract (3% rosavins, 1% salidroside) (root) 100 mg *
Damiana extract (4:1) (leaf) 75 mg *
Holy Basil extract (2% ursolic acid) (herb) 75 mg *
L-Theanine 50 mg *
Saffr' Activ® Saffron extract (0.3% safrana) (stigma) 5 mg *
Bioperine ComplexBioPerine® Black Pepper extract (95% piperine) (fruit), Ginger extract (5% gingerols) (rhizome) 3 mg *
Bioavailability Excellent

Absorption Rating

  • Vitamin D (as Cholecalciferol) Good
  • Vitamin B6 (as Pyridoxine Hydrochloride) Fair
  • Magnesium (as Magnesium Citrate) Good
  • Fish Oil (18% EPA/12% DHA) Good
  • 5-HTP (Griffonia simplicifolia) (seed) Good
  • Lemon Balm extract (4:1) (aerial) Good
  • Rhodiola extract (3% rosavins, 1% salidroside) (root) Good
  • Damiana extract (4:1) (leaf) Fair
  • Holy Basil extract (2% ursolic acid) (herb) Good
  • L-Theanine Good
  • Saffr' Activ® Saffron extract (0.3% safrana) (stigma) Good
  • Bioperine ComplexBioPerine® Black Pepper extract (95% piperine) (fruit), Ginger extract (5% gingerols) (rhizome) Good
Other Ingredients Good

Fillers & Additives

  • Gelatin
  • Purified Water
  • Glycerin
  • Beeswax
  • Soy Lecithin
  • Maltodextrin
  • Turmeric
  • Silicon Dioxide
  • Titanium Dioxide High
  • Sodium copper chlorophyllin and Microcrystalline cellulose
Efficacy Very Poor

Dosage Analysis

  • Vitamin D (as Cholecalciferol) 500 IU Under-dosed
  • Vitamin B6 (as Pyridoxine Hydrochloride) 10 mg Effective
  • Magnesium (as Magnesium Citrate) 50 mg Under-dosed
  • Fish Oil (18% EPA/12% DHA) 600 mg Effective
  • 5-HTP (Griffonia simplicifolia) (seed) 100 mg Under-dosed
  • Lemon Balm extract (4:1) (aerial) 100 mg Under-dosed
  • Rhodiola extract (3% rosavins, 1% salidroside) (root) 100 mg Under-dosed
  • Holy Basil extract (2% ursolic acid) (herb) 75 mg Under-dosed
  • L-Theanine 50 mg Under-dosed
  • Saffr' Activ® Saffron extract (0.3% safrana) (stigma) 5 mg Under-dosed
  • Bioperine ComplexBioPerine® Black Pepper extract (95% piperine) (fruit), Ginger extract (5% gingerols) (rhizome) 3 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Vitamin D (as Cholecalciferol) 500 IU 125%
Vitamin B6 (as Pyridoxine Hydrochloride) 10 mg 500%
Magnesium (as Magnesium Citrate) 50 mg 12%
Fish Oil (18% EPA/12% DHA) 600 mg *
5-HTP (Griffonia simplicifolia) (seed) 100 mg *
Lemon Balm extract (4:1) (aerial) 100 mg *
Rhodiola extract (3% rosavins, 1% salidroside) (root) 100 mg *
Damiana extract (4:1) (leaf) 75 mg *
Holy Basil extract (2% ursolic acid) (herb) 75 mg *
L-Theanine 50 mg *
Saffr' Activ® Saffron extract (0.3% safrana) (stigma) 5 mg *
Bioperine ComplexBioPerine® Black Pepper extract (95% piperine) (fruit), Ginger extract (5% gingerols) (rhizome) 3 mg *

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Gelatin Safe

Forms the capsule shell that holds the supplement contents.

Purified Water Safe

Dissolves and carries water-soluble ingredients.

Glycerin Safe

Retains moisture and helps dissolve ingredients in softgels and liquids.

Beeswax Safe

Used as a coating and to help form softgel capsules.

Soy Lecithin Safe

Helps blend oil and water-based ingredients. Common allergen.

Maltodextrin Generally_safe

Helps carry and stabilize active ingredients. Provides bulk.

Turmeric Safe

Provides natural yellow color.

Silicon Dioxide Safe

Prevents clumping and ensures consistent dosing.

Titanium Dioxide Caution

Used as a whitening agent in tablet coatings and capsules.

Sodium copper chlorophyllin and Microcrystalline cellulose Unknown

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$22$21$20$19$18 Mar 12 $19.99
Vitacost

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Irwin Naturals

Founded 1994 · Los Angeles, California, United States · 130 products · irwinnaturals.com/

Certifications

1 certification
Nsf Gmp Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Coa Availability — Verified Source
Testing Lab Disclosure — Claimed

Violation History

2 incidents
Lawsuit Deceptively marketing products as 'natural' while they contain synthetic ingredients.2021Source
Prop 65 Lead2011-02-02Source
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Frequently Asked Questions
Is Irwin Naturals Double Potency 5-HTP Extra™, 60 Liquid Softgels a good supplement?

Irwin Naturals Double Potency 5-HTP Extra™, 60 Liquid Softgels received a product quality score of 64/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 12 active ingredients with 30 servings per container. Of the 10 inactive ingredients, 7 are rated safe and 1 are flagged for review. The manufacturer, Irwin Naturals, holds a brand trust score of 78/100 with 1 verified certifications including Nsf Gmp.

What are the ingredients in Irwin Naturals Double Potency 5-HTP Extra™, 60 Liquid Softgels?

Irwin Naturals Double Potency 5-HTP Extra™, 60 Liquid Softgels contains 12 active ingredients: Vitamin D (as Cholecalciferol) (500 IU), Vitamin B6 (as Pyridoxine Hydrochloride) (10 mg), Magnesium (as Magnesium Citrate) (50 mg), Fish Oil (18% EPA/12% DHA) (600 mg), 5-HTP (Griffonia simplicifolia) (seed) (100 mg), Lemon Balm extract (4:1) (aerial) (100 mg), and 6 more. Notable high-dose ingredients include Vitamin B6 at 500% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Irwin Naturals Double Potency 5-HTP Extra™, 60 Liquid Softgels safe to take?

Irwin Naturals Double Potency 5-HTP Extra™, 60 Liquid Softgels has been analyzed for ingredient safety across all its components. Of 10 inactive ingredients, 7 are rated safe. 1 ingredient is flagged for review: Titanium Dioxide. 'Caution' doesn't mean dangerous — it indicates the ingredient has some considerations worth being aware of, such as potential sensitivities or ongoing research. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Irwin Naturals a trustworthy supplement brand?

Irwin Naturals receives a brand trust score of 78/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1994 and headquartered in Los Angeles, California, United States, the company offers 130 products in their lineup. They hold 1 verified certifications including Nsf Gmp. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Irwin Naturals has 2 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.