Irwin Naturals 2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels supplement bottle
Irwin Naturals

2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels

What We Researched
27 active ingredients analyzed · 12 inactive ingredients decoded · 1 brand certification checked · 4 retailers compared · Last updated: Mar 2026
72
Product Score Fair
78
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Total Carbohydrates 3 g <1%**
Vitamin C (as Ascorbic Acid) 50 mg 56%
Vitamin D (as Cholecalciferol) (160 IU) 4 mcg 20%
Vitamin B6 (as Pyridoxine Hydrochloride) 15 mg 882%
Vitamin B12 (as Methylcobalamin) 250 mcg 10,417%
Magnesium (as Magnesium Citrate) 12.5 mg 3%
Zinc (as Zinc Citrate) 7.5 mg 68%
Selenium (as L-Selenomethionine) 50 mcg 91%
Potassium (as Potassium Citrate) 25 mg <1%
Fish Oil (18% EPA, 288 mg, 12% DHA, 192 mg) 1600 mg
Milk Thistle extract (45% Silymarin, 121.5 mg)(seed) 270 mg
Pacran® SP Cranberry (Vaccinium macrocarpon) powder (50:1)(1.5% proanthocyanidins, 3.75 mg)(fruit) 250 mg
Artichoke extract (4:1)(leaf) 187.5 mg
Stinging Nettle extract (10:1)(leaf) 150 mg
Barberry extract (6:1)(root) 100 mg
Corn Silk extract (4:1)(stigma) 100 mg
Black Elderberry (European Elder) (Sambucus nigra) extract (10:1)(fruit) 65 mg
Dandelion (Taraxacum mongolicum) extract (4:1)(leaf) 50 mg
Uva Ursi extract (4:1)(leaf) 50 mg
N-Acetyl-Cysteine (NAC) (fermented) 45 mg
Reishi mushroom (Ganoderma lucidum) extract (fruiting body) 15 mg
BioPerine ComplexBioPerine® Black Pepper extract (95% piperine)(fruit)Ginger extract (5% gingerols)(rhizome) 3 mg
Bioavailability Very Good

Absorption Rating

  • Total Carbohydrates Fair
  • Vitamin C (as Ascorbic Acid) Fair
  • Vitamin D (as Cholecalciferol) (160 IU) Good
  • Vitamin B6 (as Pyridoxine Hydrochloride) Fair
  • Vitamin B12 (as Methylcobalamin) Good
  • Magnesium (as Magnesium Citrate) Good
  • Zinc (as Zinc Citrate) Good
  • Selenium (as L-Selenomethionine) Good
  • Potassium (as Potassium Citrate) Good
  • Fish Oil (18% EPA, 288 mg, 12% DHA, 192 mg) Good
  • Milk Thistle extract (45% Silymarin, 121.5 mg)(seed) Good
  • Pacran® SP Cranberry (Vaccinium macrocarpon) powder (50:1)(1.5% proanthocyanidins, 3.75 mg)(fruit) Fair
  • Artichoke extract (4:1)(leaf) Good
  • Stinging Nettle extract (10:1)(leaf) Fair
  • Barberry extract (6:1)(root) Good
  • Corn Silk extract (4:1)(stigma) Fair
  • Black Elderberry (European Elder) (Sambucus nigra) extract (10:1)(fruit) Fair
  • Dandelion (Taraxacum mongolicum) extract (4:1)(leaf) Fair
  • Uva Ursi extract (4:1)(leaf) Fair
  • N-Acetyl-Cysteine (NAC) (fermented) Good
  • Reishi mushroom (Ganoderma lucidum) extract (fruiting body) Fair
  • BioPerine ComplexBioPerine® Black Pepper extract (95% piperine)(fruit)Ginger extract (5% gingerols)(rhizome) Good
Other Ingredients Very Good

Fillers & Additives

  • Gelatin
  • Purified Water
  • Glycerin
  • Beeswax
  • Mannitol
  • Soy Lecithin
  • Annatto (Color)
  • Dextrin
  • Turmeric (Color)
  • Titanium Dioxide (Color) Medium
  • Maltodextrin
  • Silicon dioxide and sodium copper chlorophyllin (color)
Efficacy Poor

Dosage Analysis

  • Vitamin C (as Ascorbic Acid) 50 mg Under-dosed
  • Vitamin D (as Cholecalciferol) (160 IU) 4 mcg Under-dosed
  • Vitamin B6 (as Pyridoxine Hydrochloride) 15 mg Effective
  • Vitamin B12 (as Methylcobalamin) 250 mcg Effective
  • Magnesium (as Magnesium Citrate) 12.5 mg Under-dosed
  • Zinc (as Zinc Citrate) 7.5 mg Under-dosed
  • Selenium (as L-Selenomethionine) 50 mcg Effective
  • Potassium (as Potassium Citrate) 25 mg Under-dosed
  • Fish Oil (18% EPA, 288 mg, 12% DHA, 192 mg) 1600 mg Effective
  • Milk Thistle extract (45% Silymarin, 121.5 mg)(seed) 270 mg Effective
  • Pacran® SP Cranberry (Vaccinium macrocarpon) powder (50:1)(1.5% proanthocyanidins, 3.75 mg)(fruit) 250 mg High
  • Artichoke extract (4:1)(leaf) 187.5 mg Under-dosed
  • Stinging Nettle extract (10:1)(leaf) 150 mg Under-dosed
  • Barberry extract (6:1)(root) 100 mg Under-dosed
  • Corn Silk extract (4:1)(stigma) 100 mg Under-dosed
  • Dandelion (Taraxacum mongolicum) extract (4:1)(leaf) 50 mg Under-dosed
  • Uva Ursi extract (4:1)(leaf) 50 mg Under-dosed
  • N-Acetyl-Cysteine (NAC) (fermented) 45 mg Under-dosed
  • Reishi mushroom (Ganoderma lucidum) extract (fruiting body) 15 mg Under-dosed
  • BioPerine ComplexBioPerine® Black Pepper extract (95% piperine)(fruit)Ginger extract (5% gingerols)(rhizome) 3 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Calories 30
Total Fat 2 g 2%**
Saturated Fat 0.5 g 3%**
Cholesterol 20 mg 7%
Total Carbohydrates 3 g <1%**
Protein 1 g
Vitamin C (as Ascorbic Acid) 50 mg 56%
Vitamin D (as Cholecalciferol) (160 IU) 4 mcg 20%
Vitamin B6 (as Pyridoxine Hydrochloride) 15 mg 882%
Vitamin B12 (as Methylcobalamin) 250 mcg 10,417%
Magnesium (as Magnesium Citrate) 12.5 mg 3%
Zinc (as Zinc Citrate) 7.5 mg 68%
Selenium (as L-Selenomethionine) 50 mcg 91%
Potassium (as Potassium Citrate) 25 mg <1%
Fish Oil (18% EPA, 288 mg, 12% DHA, 192 mg) 1600 mg
Milk Thistle extract (45% Silymarin, 121.5 mg)(seed) 270 mg
Pacran® SP Cranberry (Vaccinium macrocarpon) powder (50:1)(1.5% proanthocyanidins, 3.75 mg)(fruit) 250 mg
Artichoke extract (4:1)(leaf) 187.5 mg
Stinging Nettle extract (10:1)(leaf) 150 mg
Barberry extract (6:1)(root) 100 mg
Corn Silk extract (4:1)(stigma) 100 mg
Black Elderberry (European Elder) (Sambucus nigra) extract (10:1)(fruit) 65 mg
Dandelion (Taraxacum mongolicum) extract (4:1)(leaf) 50 mg
Uva Ursi extract (4:1)(leaf) 50 mg
N-Acetyl-Cysteine (NAC) (fermented) 45 mg
Reishi mushroom (Ganoderma lucidum) extract (fruiting body) 15 mg
BioPerine ComplexBioPerine® Black Pepper extract (95% piperine)(fruit)Ginger extract (5% gingerols)(rhizome) 3 mg

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Gelatin Safe

Forms the capsule shell that holds the supplement contents.

Purified Water Safe

Dissolves and carries water-soluble ingredients.

Glycerin Safe

Retains moisture and helps dissolve ingredients in softgels and liquids.

Beeswax Safe

Used as a coating and to help form softgel capsules.

Mannitol Generally_safe

It is used as a sweetener, filler, and flow agent.

Soy Lecithin Safe

Helps blend oil and water-based ingredients. Common allergen.

Annatto (Color) Generally_safe

It is used as a natural food coloring to provide a yellow or orange hue.

Dextrin Generally_safe

It is used as a filler, binder, or coating agent.

Turmeric (Color) Safe

It is used to add yellow color to supplements.

Titanium Dioxide (Color) Caution

It is used to improve the appearance of the supplement.

Maltodextrin Generally_safe

Helps carry and stabilize active ingredients. Provides bulk.

Silicon dioxide and sodium copper chlorophyllin (color) Unknown

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$27$26$25$24$23 Mar 12 $24.99$24.99
iHerb
Vitacost

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
Irwin Naturals

Founded 1994 · Los Angeles, California, United States · 130 products · irwinnaturals.com/

Certifications

1 certification
Nsf Gmp Verified Source

Transparency

4 claims
Third Party Testing Claim — Verified Source
Coa Availability — Verified Source
Testing Lab Disclosure — Claimed

Violation History

2 incidents
Lawsuit Deceptively marketing products as 'natural' while they contain synthetic ingredients.2021Source
Prop 65 Lead2011-02-02Source
Related Supplements
Frequently Asked Questions
Is Irwin Naturals 2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels a good supplement?

Irwin Naturals 2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels received a product quality score of 72/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 27 active ingredients with 20 servings per container. Of the 12 inactive ingredients, 6 are rated safe and 1 are flagged for review. The manufacturer, Irwin Naturals, holds a brand trust score of 78/100 with 1 verified certifications including Nsf Gmp.

What are the ingredients in Irwin Naturals 2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels?

Irwin Naturals 2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels contains 27 active ingredients: Calories (30), Total Fat (2 g), Saturated Fat (0.5 g), Cholesterol (20 mg), Total Carbohydrates (3 g), Protein (1 g), and 21 more. Notable high-dose ingredients include Vitamin B6 at 882% DV, Vitamin B12 at 10,417% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is Irwin Naturals 2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels safe to take?

Irwin Naturals 2-In-1 Kidney & Liver Super Cleanse™, 60 Liquid Soft-Gels has been analyzed for ingredient safety across all its components. Of 12 inactive ingredients, 6 are rated safe. 1 ingredient is flagged for review: Titanium Dioxide (Color). 'Caution' doesn't mean dangerous — it indicates the ingredient has some considerations worth being aware of, such as potential sensitivities or ongoing research. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is Irwin Naturals a trustworthy supplement brand?

Irwin Naturals receives a brand trust score of 78/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1994 and headquartered in Los Angeles, California, United States, the company offers 130 products in their lineup. They hold 1 verified certifications including Nsf Gmp. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: Irwin Naturals has 2 historical regulatory incidents on record, which are factored into the trust score.

Scan Any Supplement Instantly

Download GoodSupp to scan barcodes, check ingredient safety, and find the best supplements for your needs.

Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.