21st Century Therapeutic-M, 130 Tablets supplement bottle
21st Century

Therapeutic-M, 130 Tablets

What We Researched
30 active ingredients analyzed · 11 inactive ingredients decoded · 2 brand certifications checked · 2 retailers compared · Last updated: Mar 2026
66
Product Score Fair
76
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin A (as Acetate & 20% as Beta-Carotene) 1,500 mcg 167%
Vitamin C (as Ascorbic Acid) 90 mg 100%
Vitamin D3 (as Cholecalciferol) (400 IU) 10 mcg 50%
Vitamin E (as dl-Alpha Tocopheryl Acetate) 27 mg 180%
Vitamin K (as Phytonadione) 28 mcg 23%
Thiamin (as Thiamin HCl, B-1) 3 mg 250%
Riboflavin (Vitamin B2) 3.4 mg 262%
Niacin (as Niacinamide) 20 mg 125%
Vitamin B-6 (as Pyridoxine HCl) 6 mg 353%
Folate (400 mcg Folic Acid) 667 mcg DFE 167%
Vitamin B-12 (as Cyanocobalamin) 12 mcg 500%
Biotin 30 mcg 100%
Pantothenic Acid (as d-Calcium Pantothenate) 10 mg 200%
Calcium (as Calcium Carbonate & Dicalcium Phosphate) 145 mg 11%
Iron (as Ferrous Fumarate) 9 mg 50%
Phosphorus (as Dicalcium Phosphate) 35 mg 3%
Iodine (as Potassium Iodide) 150 mcg 100%
Magnesium (as Magnesium Oxide) 100 mg 24%
Zinc (as Zinc Oxide) 15 mg 136%
Selenium (as Sodium Selenate) 70 mcg 127%
Copper (as Cupric Oxide) 2 mg 222%
Manganese (as Manganese Sulfate) 2 mg 87%
Chromium (as Chromium Chloride) 50 mcg 143%
Molybdenum (as Sodium Molybdate) 75 mcg 167%
Chloride (as Potassium Chloride & Pyridoxine HCl) 8 mg <1%
Potassium (as Potassium Chloride & Potassium Iodide) 11 mg <1%
Boron (as Sodium Borate) 150 mcg **
Tin (as Stannous Chloride) 10 mcg **
Silicon (as Silicon Dioxide) 2 mg **
Vanadium (as Sodium Metavanadate) 10 mcg **
Bioavailability Fair

Absorption Rating

  • Vitamin A (as Acetate & 20% as Beta-Carotene) Fair
  • Vitamin C (as Ascorbic Acid) Fair
  • Vitamin D3 (as Cholecalciferol) (400 IU) Good
  • Vitamin E (as dl-Alpha Tocopheryl Acetate) Poor
  • Vitamin K (as Phytonadione) Fair
  • Thiamin (as Thiamin HCl, B-1) Fair
  • Riboflavin (Vitamin B2) Good
  • Niacin (as Niacinamide) Good
  • Vitamin B-6 (as Pyridoxine HCl) Fair
  • Folate (400 mcg Folic Acid) Fair
  • Vitamin B-12 (as Cyanocobalamin) Fair
  • Biotin Good
  • Pantothenic Acid (as d-Calcium Pantothenate) Good
  • Calcium (as Calcium Carbonate & Dicalcium Phosphate) Fair
  • Iron (as Ferrous Fumarate) Fair
  • Phosphorus (as Dicalcium Phosphate) Good
  • Iodine (as Potassium Iodide) Good
  • Magnesium (as Magnesium Oxide) Poor
  • Zinc (as Zinc Oxide) Poor
  • Selenium (as Sodium Selenate) Fair
  • Copper (as Cupric Oxide) Poor
  • Manganese (as Manganese Sulfate) Good
  • Chromium (as Chromium Chloride) Poor
  • Molybdenum (as Sodium Molybdate) Good
  • Chloride (as Potassium Chloride & Pyridoxine HCl) Good
  • Potassium (as Potassium Chloride & Potassium Iodide) Good
  • Boron (as Sodium Borate) Fair
  • Tin (as Stannous Chloride) Poor
  • Silicon (as Silicon Dioxide) Poor
  • Vanadium (as Sodium Metavanadate) Poor
Other Ingredients Good

Fillers & Additives

  • Cellulose
  • Stearic Acid
  • Gelatin
  • Starch
  • Croscarmellose Sodium
  • Gum Acacia
  • Magnesium Silicate
  • Magnesium Stearate
  • Polyethylene Glycol Low
  • Polyvinyl Alcohol
  • Titanium Dioxide High
Efficacy Good

Dosage Analysis

  • Vitamin A (as Acetate & 20% as Beta-Carotene) 1,500 mcg Effective
  • Vitamin C (as Ascorbic Acid) 90 mg Effective
  • Vitamin D3 (as Cholecalciferol) (400 IU) 10 mcg Under-dosed
  • Vitamin E (as dl-Alpha Tocopheryl Acetate) 27 mg Effective
  • Vitamin K (as Phytonadione) 28 mcg Under-dosed
  • Thiamin (as Thiamin HCl, B-1) 3 mg Effective
  • Riboflavin (Vitamin B2) 3.4 mg Effective
  • Niacin (as Niacinamide) 20 mg Effective
  • Vitamin B-6 (as Pyridoxine HCl) 6 mg Effective
  • Folate (400 mcg Folic Acid) 667 mcg DFE Effective
  • Vitamin B-12 (as Cyanocobalamin) 12 mcg Effective
  • Biotin 30 mcg Effective
  • Pantothenic Acid (as d-Calcium Pantothenate) 10 mg Effective
  • Calcium (as Calcium Carbonate & Dicalcium Phosphate) 145 mg Under-dosed
  • Iron (as Ferrous Fumarate) 9 mg Effective
  • Phosphorus (as Dicalcium Phosphate) 35 mg Under-dosed
  • Iodine (as Potassium Iodide) 150 mcg Effective
  • Magnesium (as Magnesium Oxide) 100 mg Under-dosed
  • Zinc (as Zinc Oxide) 15 mg Effective
  • Selenium (as Sodium Selenate) 70 mcg Effective
  • Copper (as Cupric Oxide) 2 mg Effective
  • Manganese (as Manganese Sulfate) 2 mg Effective
  • Chromium (as Chromium Chloride) 50 mcg Effective
  • Molybdenum (as Sodium Molybdate) 75 mcg Effective
  • Chloride (as Potassium Chloride & Pyridoxine HCl) 8 mg Under-dosed
  • Potassium (as Potassium Chloride & Potassium Iodide) 11 mg Under-dosed
  • Boron (as Sodium Borate) 150 mcg Under-dosed
  • Silicon (as Silicon Dioxide) 2 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Vitamin A (as Acetate & 20% as Beta-Carotene) 1,500 mcg 167%
Vitamin C (as Ascorbic Acid) 90 mg 100%
Vitamin D3 (as Cholecalciferol) (400 IU) 10 mcg 50%
Vitamin E (as dl-Alpha Tocopheryl Acetate) 27 mg 180%
Vitamin K (as Phytonadione) 28 mcg 23%
Thiamin (as Thiamin HCl, B-1) 3 mg 250%
Riboflavin (Vitamin B2) 3.4 mg 262%
Niacin (as Niacinamide) 20 mg 125%
Vitamin B-6 (as Pyridoxine HCl) 6 mg 353%
Folate (400 mcg Folic Acid) 667 mcg DFE 167%
Vitamin B-12 (as Cyanocobalamin) 12 mcg 500%
Biotin 30 mcg 100%
Pantothenic Acid (as d-Calcium Pantothenate) 10 mg 200%
Calcium (as Calcium Carbonate & Dicalcium Phosphate) 145 mg 11%
Iron (as Ferrous Fumarate) 9 mg 50%
Phosphorus (as Dicalcium Phosphate) 35 mg 3%
Iodine (as Potassium Iodide) 150 mcg 100%
Magnesium (as Magnesium Oxide) 100 mg 24%
Zinc (as Zinc Oxide) 15 mg 136%
Selenium (as Sodium Selenate) 70 mcg 127%
Copper (as Cupric Oxide) 2 mg 222%
Manganese (as Manganese Sulfate) 2 mg 87%
Chromium (as Chromium Chloride) 50 mcg 143%
Molybdenum (as Sodium Molybdate) 75 mcg 167%
Chloride (as Potassium Chloride & Pyridoxine HCl) 8 mg <1%
Potassium (as Potassium Chloride & Potassium Iodide) 11 mg <1%
Boron (as Sodium Borate) 150 mcg **
Tin (as Stannous Chloride) 10 mcg **
Silicon (as Silicon Dioxide) 2 mg **
Vanadium (as Sodium Metavanadate) 10 mcg **

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Cellulose Safe

Provides bulk and structure in tablets and capsules.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Gelatin Safe

Forms the capsule shell that holds the supplement contents.

Starch Generally_safe

It is used as a filler, binder, or thickener.

Croscarmellose Sodium Safe

Helps tablets break apart and dissolve quickly in the stomach.

Gum Acacia Safe

It is used as a thickener, binder, or emulsifier.

Magnesium Silicate Generally_safe

It is used to improve powder flow and prevent clumping.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Polyethylene Glycol Caution

It is used as a binder, coating agent, or to improve solubility.

Polyvinyl Alcohol Generally_safe

It is used as a coating for tablets or capsules.

Titanium Dioxide Caution

Used as a whitening agent in tablet coatings and capsules.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$9$8$7$6$5 Mar 12 $7.00
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
21st Century

Founded 1991 · Tempe, Arizona, United States · 231 products · 21stcenturyvitamins.com/

Certifications

2 certifications
Consumerlab Verified
Nsf Gmp Verified Source

Transparency

4 claims
Third Party Testing Claim — Claimed Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

4 incidents
Prop 65 Lead2021-06-22Source
Recall Vitamin D3 5000 IU Tablets2021-05-19Source
Lawsuit False advertising of Glucosamine/Chondroitin supplements.2012Source
Prop 65 Lead2008-12-23Source
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Frequently Asked Questions
Is 21st Century Therapeutic-M, 130 Tablets a good supplement?

21st Century Therapeutic-M, 130 Tablets received a product quality score of 66/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 30 active ingredients Of the 11 inactive ingredients, 6 are rated safe and 2 are flagged for review. The manufacturer, 21st Century, holds a brand trust score of 76/100 with 2 verified certifications including Consumerlab, Nsf Gmp.

What are the ingredients in 21st Century Therapeutic-M, 130 Tablets?

21st Century Therapeutic-M, 130 Tablets contains 30 active ingredients: Vitamin A (as Acetate & 20% as Beta-Carotene) (1,500 mcg), Vitamin C (as Ascorbic Acid) (90 mg), Vitamin D3 (as Cholecalciferol) (400 IU) (10 mcg), Vitamin E (as dl-Alpha Tocopheryl Acetate) (27 mg), Vitamin K (as Phytonadione) (28 mcg), Thiamin (as Thiamin HCl, B-1) (3 mg), and 24 more. Notable high-dose ingredients include Thiamin at 250% DV, Riboflavin at 262% DV, Vitamin B-6 at 353% DV. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is 21st Century Therapeutic-M, 130 Tablets safe to take?

21st Century Therapeutic-M, 130 Tablets has been analyzed for ingredient safety across all its components. Of 11 inactive ingredients, 6 are rated safe. 2 ingredients are flagged for review: Polyethylene Glycol, Titanium Dioxide. 'Caution' doesn't mean dangerous — it indicates the ingredient has some considerations worth being aware of, such as potential sensitivities or ongoing research. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is 21st Century a trustworthy supplement brand?

21st Century receives a brand trust score of 76/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1991 and headquartered in Tempe, Arizona, United States, the company offers 231 products in their lineup. They hold 2 verified certifications including Consumerlab, Nsf Gmp. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: 21st Century has 4 historical regulatory incidents on record, which are factored into the trust score.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.