21st Century Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength, 80 Tablets supplement bottle
21st Century

Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength, 80 Tablets

What We Researched
10 active ingredients analyzed · 13 inactive ingredients decoded · 2 brand certifications checked · 3 retailers compared · Last updated: Mar 2026
56
Product Score Poor
76
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Vitamin C (as Ascorbic Acid) 60 mg 70%
Manganese (as Manganese Sulfate) 2 mg 90%
Glucosamine HCl 1,500 mg **
Proprietary BlendChondroitin Sulfate, Methylsulfonylmethane (MSM), Hydrolyzed Collagen, Boswellia serrata (root), Vitamin C, Manganese, Hyaluronic Acid 1,250 mg **
Boswellia serrata Extract 100 mg **
Boron (as Sodium Borate) 3 mg **
Bioavailability Very Good

Absorption Rating

  • Vitamin C (as Ascorbic Acid) Fair
  • Manganese (as Manganese Sulfate) Good
  • Glucosamine HCl Fair
  • Proprietary BlendChondroitin Sulfate, Methylsulfonylmethane (MSM), Hydrolyzed Collagen, Boswellia serrata (root), Vitamin C, Manganese, Hyaluronic Acid Good
  • Boswellia serrata Extract Good
  • Boron (as Sodium Borate) Fair
Other Ingredients Very Poor

Fillers & Additives

  • Cellulose
  • Polyplasdone
  • Artificial colors (FD&C Red #40, FD&C blue #2 carmine, FD&C yellow #5) High
  • Dextrin
  • Hydroxypropyl Methylcellulose
  • Magnesium Stearate
  • Maltodextrin
  • PEG Medium
  • Polyvinyl Alcohol
  • Silicon Dioxide
  • Stearic Acid
  • Talc High
  • Titanium Dioxide High
Efficacy Fair

Dosage Analysis

  • Vitamin C (as Ascorbic Acid) 60 mg Under-dosed
  • Manganese (as Manganese Sulfate) 2 mg Effective
  • Glucosamine HCl 1,500 mg Effective
  • Proprietary BlendChondroitin Sulfate, Methylsulfonylmethane (MSM), Hydrolyzed Collagen, Boswellia serrata (root), Vitamin C, Manganese, Hyaluronic Acid 1,250 mg Under-dosed
  • Boswellia serrata Extract 100 mg Under-dosed
  • Boron (as Sodium Borate) 3 mg Effective

Supplement Facts

Ingredient Amount % Daily Value
Calories 10
Total Carbohydrate 2 g <1%‡
Total Sugars 1 g **
Vitamin C (as Ascorbic Acid) 60 mg 70%
Manganese (as Manganese Sulfate) 2 mg 90%
Sodium 50 mg 2%
Glucosamine HCl 1,500 mg **
Proprietary BlendChondroitin Sulfate, Methylsulfonylmethane (MSM), Hydrolyzed Collagen, Boswellia serrata (root), Vitamin C, Manganese, Hyaluronic Acid 1,250 mg **
Boswellia serrata Extract 100 mg **
Boron (as Sodium Borate) 3 mg **

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Cellulose Safe

Provides bulk and structure in tablets and capsules.

Polyplasdone Generally_safe

It is used to help tablets and capsules break down in the body.

Artificial colors (FD&C Red #40, FD&C blue #2 carmine, FD&C yellow #5) Unknown
Dextrin Generally_safe

It is used as a filler, binder, or coating agent.

Hydroxypropyl Methylcellulose Safe

It is used as a coating for tablets and capsules.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Maltodextrin Generally_safe

Helps carry and stabilize active ingredients. Provides bulk.

PEG Caution

It is used as a binder, coating, or emulsifier.

Polyvinyl Alcohol Generally_safe

It is used as a coating for tablets or capsules.

Silicon Dioxide Safe

Prevents clumping and ensures consistent dosing.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Talc Avoid

It is used to improve powder flow and prevent clumping.

Titanium Dioxide Caution

Used as a whitening agent in tablet coatings and capsules.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$17$16$15$14$13 Mar 12 $15.00
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
21st Century

Founded 1991 · Tempe, Arizona, United States · 231 products · 21stcenturyvitamins.com/

Certifications

2 certifications
Consumerlab Verified
Nsf Gmp Verified Source

Transparency

4 claims
Third Party Testing Claim — Claimed Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

4 incidents
Prop 65 Lead2021-06-22Source
Recall Vitamin D3 5000 IU Tablets2021-05-19Source
Lawsuit False advertising of Glucosamine/Chondroitin supplements.2012Source
Prop 65 Lead2008-12-23Source
Related Supplements
Frequently Asked Questions
Is 21st Century Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength a good supplement?

21st Century Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength, 80 Tablets received a product quality score of 56/100 in GoodSupp's independent analysis, indicating several areas of concern that consumers should review. The product contains 10 active ingredients with 40 servings per container. Of the 13 inactive ingredients, 5 are rated safe and 2 are flagged for review. The manufacturer, 21st Century, holds a brand trust score of 76/100 with 2 verified certifications including Consumerlab, Nsf Gmp.

What are the ingredients in 21st Century Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength?

21st Century Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength contains 10 active ingredients: Calories (10), Total Carbohydrate (2 g), Total Sugars (1 g), Vitamin C (as Ascorbic Acid) (60 mg), Manganese (as Manganese Sulfate) (2 mg), Sodium (50 mg), and 4 more. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is 21st Century Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength safe to take?

21st Century Glucosamine Chondroitin Complex Plus MSM, Advanced Triple Strength, 80 Tablets has been analyzed for ingredient safety across all its components. Of 13 inactive ingredients, 5 are rated safe. 2 ingredients are flagged for review: PEG, Titanium Dioxide. 'Caution' doesn't mean dangerous — it indicates the ingredient has some considerations worth being aware of, such as potential sensitivities or ongoing research. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is 21st Century a trustworthy supplement brand?

21st Century receives a brand trust score of 76/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1991 and headquartered in Tempe, Arizona, United States, the company offers 231 products in their lineup. They hold 2 verified certifications including Consumerlab, Nsf Gmp. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: 21st Century has 4 historical regulatory incidents on record, which are factored into the trust score.

How to take turmeric?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

How to use turmeric?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

How to take turmeric for inflammation?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

Scan Any Supplement Instantly

Download GoodSupp to scan barcodes, check ingredient safety, and find the best supplements for your needs.

Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.