21st Century Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets supplement bottle
21st Century

Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets

What We Researched
8 active ingredients analyzed · 9 inactive ingredients decoded · 2 brand certifications checked · 3 retailers compared · Last updated: Mar 2026
71
Product Score Fair
76
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Glucosamine HCl 1,500 mg **
Chondroitin Sulfate 1,200 mg **
MSM (Methylsulfonylmethane) 500 mg **
Proprietary BlendSilica & Hyaluronic Acid (as Sodium Hyaluronate) 60 mg **
Bioavailability Very Good

Absorption Rating

  • Glucosamine HCl Fair
  • Chondroitin Sulfate Good
  • MSM (Methylsulfonylmethane) Good
  • Proprietary BlendSilica & Hyaluronic Acid (as Sodium Hyaluronate) Fair
Other Ingredients Good

Fillers & Additives

  • Cellulose
  • Polyplasdone
  • Stearic Acid
  • Croscarmellose Sodium
  • Magnesium Silicate
  • Magnesium Stearate
  • Polyethylene Glycol Low
  • Polyvinyl Alcohol
  • Titanium Dioxide High
Efficacy Good

Dosage Analysis

  • Glucosamine HCl 1,500 mg Effective
  • Chondroitin Sulfate 1,200 mg Effective
  • MSM (Methylsulfonylmethane) 500 mg Under-dosed

Supplement Facts

Ingredient Amount % Daily Value
Calories 10
Total Carbohydrate 3 g 1%‡
Total Sugars 1 g **
Sodium 120 mg 5%
Glucosamine HCl 1,500 mg **
Chondroitin Sulfate 1,200 mg **
MSM (Methylsulfonylmethane) 500 mg **
Proprietary BlendSilica & Hyaluronic Acid (as Sodium Hyaluronate) 60 mg **

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Cellulose Safe

Provides bulk and structure in tablets and capsules.

Polyplasdone Generally_safe

It is used to help tablets and capsules break down in the body.

Stearic Acid Safe

Helps ingredients flow smoothly through manufacturing equipment.

Croscarmellose Sodium Safe

Helps tablets break apart and dissolve quickly in the stomach.

Magnesium Silicate Generally_safe

It is used to improve powder flow and prevent clumping.

Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Polyethylene Glycol Caution

It is used as a binder, coating agent, or to improve solubility.

Polyvinyl Alcohol Generally_safe

It is used as a coating for tablets or capsules.

Titanium Dioxide Caution

Used as a whitening agent in tablet coatings and capsules.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$27$26$25$24$23 Mar 12 $25.00
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
21st Century

Founded 1991 · Tempe, Arizona, United States · 231 products · 21stcenturyvitamins.com/

Certifications

2 certifications
Consumerlab Verified
Nsf Gmp Verified Source

Transparency

4 claims
Third Party Testing Claim — Claimed Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

4 incidents
Prop 65 Lead2021-06-22Source
Recall Vitamin D3 5000 IU Tablets2021-05-19Source
Lawsuit False advertising of Glucosamine/Chondroitin supplements.2012Source
Prop 65 Lead2008-12-23Source
Related Supplements
Frequently Asked Questions
Is 21st Century Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets a good supplement?

21st Century Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets received a product quality score of 71/100 in GoodSupp's independent analysis, suggesting some areas that could be improved. The product contains 8 active ingredients with 40 servings per container. Of the 9 inactive ingredients, 4 are rated safe and 2 are flagged for review. The manufacturer, 21st Century, holds a brand trust score of 76/100 with 2 verified certifications including Consumerlab, Nsf Gmp.

What are the ingredients in 21st Century Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets?

21st Century Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets contains 8 active ingredients: Calories (10), Total Carbohydrate (3 g), Total Sugars (1 g), Sodium (120 mg), Glucosamine HCl (1,500 mg), Chondroitin Sulfate (1,200 mg), and 2 more. Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is 21st Century Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets safe to take?

21st Century Glucosamine & Chondroitin plus Hyaluronic Acid + MSM, 120 Tablets has been analyzed for ingredient safety across all its components. Of 9 inactive ingredients, 4 are rated safe. 2 ingredients are flagged for review: Polyethylene Glycol, Titanium Dioxide. 'Caution' doesn't mean dangerous — it indicates the ingredient has some considerations worth being aware of, such as potential sensitivities or ongoing research. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is 21st Century a trustworthy supplement brand?

21st Century receives a brand trust score of 76/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1991 and headquartered in Tempe, Arizona, United States, the company offers 231 products in their lineup. They hold 2 verified certifications including Consumerlab, Nsf Gmp. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: 21st Century has 4 historical regulatory incidents on record, which are factored into the trust score.

How to take turmeric?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

How to use turmeric?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

How to take turmeric for inflammation?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

Scan Any Supplement Instantly

Download GoodSupp to scan barcodes, check ingredient safety, and find the best supplements for your needs.

Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.