21st Century Digestive Enzymes, 60 Capsules supplement bottle
21st Century

Digestive Enzymes, 60 Capsules

What We Researched
1 active ingredient analyzed · 6 inactive ingredients decoded · 2 brand certifications checked · 3 retailers compared · Last updated: Mar 2026
100
Product Score Excellent
76
Brand Score Fair

Product Analysis

Transparency Excellent

Supplement Facts

IngredientAmount% DV
Proprietary Digestive Enzyme BlendAmylase, Protease, Lipase, Invertase, Lactase, Maltase, Cellulase 220 mg **
Bioavailability Excellent

Absorption Rating

  • Proprietary Digestive Enzyme BlendAmylase, Protease, Lipase, Invertase, Lactase, Maltase, Cellulase Good
Other Ingredients Excellent

Fillers & Additives

  • Oat Fiber
  • Gelatin
  • Silicon Dioxide
  • Magnesium Silicate
  • Trace mineral complex
  • Magnesium Stearate
Efficacy N/A

Dosage Analysis

Dosage data not available for assessment.

Supplement Facts

Ingredient Amount % Daily Value
Proprietary Digestive Enzyme BlendAmylase, Protease, Lipase, Invertase, Lactase, Maltase, Cellulase 220 mg **

Other Ingredients

Inactive ingredients used in manufacturing. All rated for safety.

Oat Fiber Generally_safe

It is used as a filler or source of fiber.

Gelatin Safe

Forms the capsule shell that holds the supplement contents.

Silicon Dioxide Safe

Prevents clumping and ensures consistent dosing.

Magnesium Silicate Generally_safe

It is used to improve powder flow and prevent clumping.

Trace mineral complex Unknown
Magnesium Stearate Safe

Prevents ingredients from sticking to manufacturing equipment during tableting.

Price Comparison

Price History

Tracked across major retailers. Updated periodically.

$9$8$7$6$5 Mar 12 $7.49
iHerb

Prices shown at time of last check. Click a retailer to see current price. GoodSupp is not affiliated with any retailer.

Brand Trust Report
21st Century

Founded 1991 · Tempe, Arizona, United States · 231 products · 21stcenturyvitamins.com/

Certifications

2 certifications
Consumerlab Verified
Nsf Gmp Verified Source

Transparency

4 claims
Third Party Testing Claim — Claimed Source
Testing Lab Disclosure — Verified Source
In House Testing — Verified Source

Violation History

4 incidents
Prop 65 Lead2021-06-22Source
Recall Vitamin D3 5000 IU Tablets2021-05-19Source
Lawsuit False advertising of Glucosamine/Chondroitin supplements.2012Source
Prop 65 Lead2008-12-23Source
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Frequently Asked Questions
Is 21st Century Digestive Enzymes, 60 Capsules a good supplement?

21st Century Digestive Enzymes, 60 Capsules received a product quality score of 100/100 in GoodSupp's independent analysis, placing it in the top tier of supplements we've analyzed. The product contains 1 active ingredients Of the 6 inactive ingredients, 3 are rated safe and 0 are flagged for review. The manufacturer, 21st Century, holds a brand trust score of 76/100 with 2 verified certifications including Consumerlab, Nsf Gmp.

What are the ingredients in 21st Century Digestive Enzymes, 60 Capsules?

21st Century Digestive Enzymes, 60 Capsules contains 1 active ingredients: Proprietary Digestive Enzyme BlendAmylase, Protease, Lipase, Invertase, Lactase, Maltase, Cellulase (220 mg). Each ingredient's dosage, form, and safety rating is analyzed independently in GoodSupp's full product breakdown.

Is 21st Century Digestive Enzymes, 60 Capsules safe to take?

21st Century Digestive Enzymes, 60 Capsules has been analyzed for ingredient safety across all its components. Always consult your healthcare provider before starting any new supplement, especially if you take medications or have underlying health conditions.

Is 21st Century a trustworthy supplement brand?

21st Century receives a brand trust score of 76/100 based on GoodSupp's independent analysis of certifications, regulatory history, and transparency practices. Founded in 1991 and headquartered in Tempe, Arizona, United States, the company offers 231 products in their lineup. They hold 2 verified certifications including Consumerlab, Nsf Gmp. Third-party certifications are independently verified and indicate the brand meets specific quality, purity, and manufacturing standards. Note: 21st Century has 4 historical regulatory incidents on record, which are factored into the trust score.

When to take digestive enzymes?

Timing can affect how well your body absorbs and utilizes supplements. As a general rule: fat-soluble vitamins (A, D, E, K) and omega-3s are best taken with meals containing fat. Water-soluble vitamins (B vitamins, vitamin C) can be taken anytime but are often recommended with breakfast. Minerals like calcium and magnesium may be better absorbed when split between meals. Iron absorbs best on an empty stomach but can cause nausea — taking it with vitamin C improves absorption while reducing stomach upset. Probiotics are often recommended on an empty stomach (before breakfast) for optimal survival through stomach acid. Consistency matters more than perfect timing — taking supplements at the same time each day helps build a reliable habit.

Do digestive enzymes make you poop more?

The effects of supplements on the body vary based on the specific ingredients, dosages, and individual factors. Quality clinical research is the best guide for understanding what supplements actually do versus marketing claims. Be cautious of products that promise dramatic results — legitimate supplements support health gradually, not overnight. Checking the ingredient label, understanding the dosages, and reviewing the scientific evidence are essential steps before starting any supplement. GoodSupp evaluates over 250,000 products based on published research and evidence-based criteria.

Do digestive enzymes help with bloating?

This is an important question for supplement consumers. The dietary supplement industry is largely self-regulated, which means product quality, ingredient transparency, and safety practices vary significantly between brands and products. The most reliable way to evaluate any supplement is to check for third-party testing certifications, review the full ingredient list and dosages, and research the brand's regulatory track record. GoodSupp's database of over 250,000 analyzed products provides independent quality scores, ingredient safety ratings, and brand trust reports to help you make evidence-based decisions.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.