Vitamin B12 (Cyanocobalamin)

Generally Safe MineralSynthetic

Vitamin B12 (Cyanocobalamin) is a synthetic mineral used in dietary supplements. Safety rating: Generally Safe. It is generally considered safe for most people at standard doses. Found in 20 supplements in the GoodSupp database. A synthetic form of vitamin B12.

20 Products use this
Generally Safe Safety rating
Mineral Category
No Natural origin

Safety Verdict: Generally Safe

Some individuals may have concerns about the cyanide molecule attached to the cobalamin.

What is Vitamin B12 (Cyanocobalamin)?

A synthetic form of vitamin B12.

Common Names Vitamin B12 (Cyanocobalamin), Cyanocobalamin
Type Mineral
Origin Synthetic / Manufactured
Safety Rating Generally Safe

Why is Vitamin B12 (Cyanocobalamin) used in supplements?

It is added as a source of vitamin B12.

Role in supplements: Mineral compound — provides a specific mineral in a bioavailable form the body can absorb.

Should you be concerned about Vitamin B12 (Cyanocobalamin)?

Generally no. Vitamin B12 (Cyanocobalamin) is considered safe for most people at typical supplement doses. Some individuals may want to be aware of minor sensitivities.

Some individuals may have concerns about the cyanide molecule attached to the cobalamin.

Low risk. Generally safe for most people in supplement amounts.

Top-rated products containing Vitamin B12 (Cyanocobalamin)

These 20 highest-scoring supplements in our database use Vitamin B12 (Cyanocobalamin).

Liquid I.V. Hydration Multiplier + Immune Support Powder Energy Supplements
Liquid I.V. Hydration Multiplier + Immune Support Powder Energy Supplements
Product 89 Brand N/A
Liquid I.V. Hydration Multiplier Electrolyte Drink Mix
Liquid I.V. Hydration Multiplier Electrolyte Drink Mix
Product 89 Brand N/A
HealthAid Vitamina B12 (Cianocobalamina), 1000 ug
HealthAid Vitamina B12 (Cianocobalamina), 1000 ug
Product 87 Brand N/A
Perfectil Perfectil Vitabiotics Multivitamin | Hair Growth and Thickening Formula | Supports Thicker, Healthy Hair | Vitamin D, E, Collagen, Biotin, and More
Perfectil Perfectil Vitabiotics Multivitamin | Hair Growth and Thickening Formula | Supports Thicker, Healthy Hair | Vitamin D, E, Collagen, Biotin, and More
Product 85 Brand N/A
Jointace Vitabiotics Jointace Glucosamine and Chondroitin 90 Tablets
Jointace Vitabiotics Jointace Glucosamine and Chondroitin 90 Tablets
Product 85 Brand N/A
Jointace Vitabiotics Jointace Glucosamine & Chondroitin 30 Tablets
Jointace Vitabiotics Jointace Glucosamine & Chondroitin 30 Tablets
Product 83 Brand N/A
MinaVit Multivitamins & Iron
MinaVit Multivitamins & Iron
Product 83 Brand N/A
EVLution Nutrition ENGN, Pre-Workout Engine, Blue Raz, 11 oz (312 g)
EVLution Nutrition ENGN, Pre-Workout Engine, Blue Raz, 11 oz (312 g)
Product 81 Brand N/A
One-A-Day VitaCraves®, Women's Multivitamin/Multimineral Supplement Gummies, 170 Gummies
One-A-Day VitaCraves®, Women's Multivitamin/Multimineral Supplement Gummies, 170 Gummies
Product 79 Brand N/A
Liquid I.V. Hydration Multiplier, Electrolyte Drink Mix, Passion Fruit, 10 Stick Packs, 0.56 oz (16 g) Each
Liquid I.V. Hydration Multiplier, Electrolyte Drink Mix, Passion Fruit, 10 Stick Packs, 0.56 oz (16 g) Each
Product 79 Brand N/A
Liquid I.V. Hydration Multiplier®, Electrolyte Drink Mix, Watermelon, 10 Stick Packs, 0.56 oz (16 g) Each
Liquid I.V. Hydration Multiplier®, Electrolyte Drink Mix, Watermelon, 10 Stick Packs, 0.56 oz (16 g) Each
Product 79 Brand N/A
Liquid I.V. Hydration Multiplier®, Electrolyte Drink Mix, Strawberry, 10 Stick Packs, 0.56 oz (16 g) Each
Liquid I.V. Hydration Multiplier®, Electrolyte Drink Mix, Strawberry, 10 Stick Packs, 0.56 oz (16 g) Each
Product 79 Brand N/A
Flintstones Children's Multivitamin, + Immunity Support, 150 Gummies
Flintstones Children's Multivitamin, + Immunity Support, 150 Gummies
Product 78 Brand N/A
Venture Pal Hydration Boost, Electrolyte Drink Mix, Cherry, 16 Sticks, 0.32 oz (9 g) Each
Venture Pal Hydration Boost, Electrolyte Drink Mix, Cherry, 16 Sticks, 0.32 oz (9 g) Each
Product 77 Brand N/A
Venture Pal Hydration Boost, Electrolyte Drink Mix, Variety Pack, 16 Stick Packs, 0.32 oz (9 g) Each
Venture Pal Hydration Boost, Electrolyte Drink Mix, Variety Pack, 16 Stick Packs, 0.32 oz (9 g) Each
Product 77 Brand N/A
Venture Pal Hydration Boost, Electrolyte Drink Mix, Grape, 16 Stick Packs, 0.32 oz (9 g) Each
Venture Pal Hydration Boost, Electrolyte Drink Mix, Grape, 16 Stick Packs, 0.32 oz (9 g) Each
Product 77 Brand N/A
Venture Pal Hydration Boost, Electrolyte Drink Mix, Passion Fruit, 16 Stick Packs, 0.32 oz (9 g) Each
Venture Pal Hydration Boost, Electrolyte Drink Mix, Passion Fruit, 16 Stick Packs, 0.32 oz (9 g) Each
Product 77 Brand N/A
Venture Pal Hydration Boost, Electrolyte Drink Mix, Pineapple, 16 Stick Packs, 0.32 oz (9 g) Each
Venture Pal Hydration Boost, Electrolyte Drink Mix, Pineapple, 16 Stick Packs, 0.32 oz (9 g) Each
Product 77 Brand N/A
PH PROWISE Healthcare Lions Mane Mushroom Supplement 4000mg with Vitamin B1, B6, B12 & Black Pepper - 180 Super Strength Vegan Tablets with 50% Polysaccharides (Not Powder or Capsules) | Made in The UK by Prowise
PH PROWISE Healthcare Lions Mane Mushroom Supplement 4000mg with Vitamin B1, B6, B12 & Black Pepper - 180 Super Strength Vegan Tablets with 50% Polysaccharides (Not Powder or Capsules) | Made in The UK by Prowise
Product 76 Brand N/A
The Flintstones Complete Chewable Kids Vitamins - Fruit Flavors
The Flintstones Complete Chewable Kids Vitamins - Fruit Flavors
Product 75 Brand N/A
Related Ingredients
Ancient Sea Salt Safe Ascorbic Acid (Vitamin C) Safe Biotin (Vitamin B7) Safe Calcium Ascorbate Safe Calcium Chloride Generally Safe Calcium Citrate Safe Calcium Gluconate Safe Calcium Lactate Safe
Frequently Asked Questions
Is Vitamin B12 (Cyanocobalamin) safe in supplements?

Vitamin B12 (Cyanocobalamin) is rated generally safe for most people at amounts commonly found in supplements. While the overall safety profile is favorable, some individuals may experience minor sensitivities. Some individuals may have concerns about the cyanide molecule attached to the cobalamin. In GoodSupp's database, 20 products contain this ingredient. Consult your healthcare provider if you have specific concerns.

What is Vitamin B12 (Cyanocobalamin) and why is it in my supplement?

A synthetic form of vitamin B12. It appears in 20 products in the GoodSupp database.

Is Vitamin B12 (Cyanocobalamin) natural or synthetic?

Vitamin B12 (Cyanocobalamin) is synthetically produced, meaning it is manufactured through chemical processes rather than directly extracted from natural sources. Synthetic ingredients are extremely common in supplements and are not inherently less safe than natural alternatives. In many cases, synthetic production allows for higher purity and more consistent quality. The FDA regulates both natural and synthetic supplement ingredients under the same safety standards. GoodSupp rates ingredients based on their actual safety data regardless of whether they're natural or synthetic.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.