Microcrystalline Cellulose (Plant Fiber)

Safe FillerNatural

Microcrystalline Cellulose (Plant Fiber) is a naturally derived filler used in dietary supplements. Safety rating: Safe. It is widely considered safe at typical supplement doses. Found in 20 supplements in the GoodSupp database. Microcrystalline cellulose is a purified form of cellulose derived from plant fiber used as a filler and binder.

20 Products use this
Safe Safety rating
Filler Category
Yes Natural origin

Safety Verdict: Safe

This ingredient is rated safe for use in dietary supplements.

What is Microcrystalline Cellulose (Plant Fiber)?

Microcrystalline cellulose is a purified form of cellulose derived from plant fiber used as a filler and binder.

Common Names Microcrystalline Cellulose (Plant Fiber), MCC
Type Filler
Origin Natural / Plant-derived
Safety Rating Safe

Why is Microcrystalline Cellulose (Plant Fiber) used in supplements?

It is used as a filler, binder, and disintegrant.

Role in supplements: Filler — adds bulk to fill capsules or tablets to a standard size. Does not contribute to the supplement's active benefits.

Should you be concerned about Microcrystalline Cellulose (Plant Fiber)?

No. Microcrystalline Cellulose (Plant Fiber) is widely regarded as safe for use in dietary supplements at typical levels. It has a long history of use and is accepted by major regulatory bodies.

No action needed. This ingredient is safe at amounts used in supplements.

Top-rated products containing Microcrystalline Cellulose (Plant Fiber)

These 20 highest-scoring supplements in our database use Microcrystalline Cellulose (Plant Fiber).

Swanson Lithium Orotate, 5 mg, 60 Veggie Capsules
Swanson Lithium Orotate, 5 mg, 60 Veggie Capsules
Product 100 Brand N/A
Swanson Probiotic, 120 Capsules (1 Billion CFU per Capsule)
Swanson Probiotic, 120 Capsules (1 Billion CFU per Capsule)
Product 100 Brand N/A
Swanson FemFlora, Probiotic For Women, 9.8 billion CFU, 60 Vegan Capsules
Swanson FemFlora, Probiotic For Women, 9.8 billion CFU, 60 Vegan Capsules
Product 100 Brand N/A
Swanson Zinc Picolinate, 22 mg, 60 Vegan Capsules
Swanson Zinc Picolinate, 22 mg, 60 Vegan Capsules
Product 100 Brand N/A
Swanson Magnesium Taurate, 120 tablets (100 mg per Tablet)
Swanson Magnesium Taurate, 120 tablets (100 mg per Tablet)
Product 100 Brand N/A
Swanson Zinc Citrate, 30 mg, 60 Capsules
Swanson Zinc Citrate, 30 mg, 60 Capsules
Product 100 Brand N/A
Swanson Full Spectrum® Korean Red Ginseng Root, 400 mg, 90 Capsules
Swanson Full Spectrum® Korean Red Ginseng Root, 400 mg, 90 Capsules
Product 100 Brand N/A
Swanson Cordyceps, 120 Capsules (600 mg per Capsule)
Swanson Cordyceps, 120 Capsules (600 mg per Capsule)
Product 100 Brand N/A
Swanson Phosphatidylserine, 100 mg, 30 Veggie Caps
Swanson Phosphatidylserine, 100 mg, 30 Veggie Caps
Product 100 Brand N/A
Swanson Full Spectrum® Boswellia, 60 Capsules (800 mg per Capsule)
Swanson Full Spectrum® Boswellia, 60 Capsules (800 mg per Capsule)
Product 100 Brand N/A
Swanson Albion® Copper, 2 mg, 300 Tablets
Swanson Albion® Copper, 2 mg, 300 Tablets
Product 100 Brand N/A
Olympian Labs Chromium Polynicotinate, 200 mcg, 100 Vegetarian Capsules
Olympian Labs Chromium Polynicotinate, 200 mcg, 100 Vegetarian Capsules
Product 100 Brand N/A
Swanson Lactobacillus Gasseri, 3 Billion CFU, 60 Vegan DRcaps
Swanson Lactobacillus Gasseri, 3 Billion CFU, 60 Vegan DRcaps
Product 100 Brand N/A
Swanson Lactobacillus Acidophilus, 1 Billion CFU, 100 Capsules
Swanson Lactobacillus Acidophilus, 1 Billion CFU, 100 Capsules
Product 100 Brand N/A
Swanson Full Spectrum®, Lemon Balm, 500 mg, 60 Capsules
Swanson Full Spectrum®, Lemon Balm, 500 mg, 60 Capsules
Product 100 Brand N/A
Swanson L. Plantarum Probiotic, 10 Billion CFU, 30 Vegan EMBO Caps AP
Swanson L. Plantarum Probiotic, 10 Billion CFU, 30 Vegan EMBO Caps AP
Product 100 Brand N/A
Swanson Lactobacillus Acidophilus, 1 Billion CFU, 250 Capsules
Swanson Lactobacillus Acidophilus, 1 Billion CFU, 250 Capsules
Product 100 Brand N/A
Swanson Taurine, 500 mg, 100 Capsules
Swanson Taurine, 500 mg, 100 Capsules
Product 100 Brand N/A
Swanson Olive Leaf Extract, 500 mg, 120 Capsules
Swanson Olive Leaf Extract, 500 mg, 120 Capsules
Product 100 Brand N/A
Swanson Horse Chestnut Extract, 250 mg, 120 Capsules
Swanson Horse Chestnut Extract, 250 mg, 120 Capsules
Product 100 Brand N/A
Related Ingredients
Frequently Asked Questions
Is Microcrystalline Cellulose (Plant Fiber) safe in supplements?

Yes. Microcrystalline Cellulose (Plant Fiber) is rated safe for use in dietary supplements at typical levels. This rating is based on regulatory assessments, published safety research, and its long history of use in the supplement industry. It is widely accepted by major regulatory bodies including the FDA and EFSA. In GoodSupp's database, 20 products contain this ingredient. Consult your healthcare provider if you have specific concerns.

What is Microcrystalline Cellulose (Plant Fiber) and why is it in my supplement?

Microcrystalline cellulose is a purified form of cellulose derived from plant fiber used as a filler and binder. As a filler, it adds bulk to capsules or tablets to achieve a standard size without affecting the active ingredients. It appears in 20 products in the GoodSupp database.

Is Microcrystalline Cellulose (Plant Fiber) natural or synthetic?

Microcrystalline Cellulose (Plant Fiber) is naturally derived, meaning it comes from natural sources such as plants, minerals, or animal products rather than being chemically synthesized. Natural-origin ingredients are preferred by many consumers, though it's important to note that 'natural' does not automatically mean 'safer' — safety depends on the specific substance, its purity, and the amount used. The safety rating assigned by GoodSupp is based on the ingredient's actual safety profile, not its origin.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.