Hydroxypropyl Methylcellulose (Capsule)

Safe CapsuleNatural

Hydroxypropyl Methylcellulose (Capsule) is a naturally derived capsule used in dietary supplements. Safety rating: Safe. It is widely considered safe at typical supplement doses. Found in 20 supplements in the GoodSupp database. A plant-derived polymer used to make vegetarian capsules.

20 Products use this
Safe Safety rating
Capsule Category
Yes Natural origin

Safety Verdict: Safe

This ingredient is rated safe for use in dietary supplements.

What is Hydroxypropyl Methylcellulose (Capsule)?

A plant-derived polymer used to make vegetarian capsules.

Common Names Hydroxypropyl Methylcellulose (Capsule), HPMC Capsule, Vegetarian Capsule
Type Capsule
Origin Natural / Plant-derived
Safety Rating Safe

Why is Hydroxypropyl Methylcellulose (Capsule) used in supplements?

It is used to encapsulate supplement ingredients.

Role in supplements: Capsule material — forms the shell that contains the supplement's active ingredients. Dissolves in the stomach to release contents.

Should you be concerned about Hydroxypropyl Methylcellulose (Capsule)?

No. Hydroxypropyl Methylcellulose (Capsule) is widely regarded as safe for use in dietary supplements at typical levels. It has a long history of use and is accepted by major regulatory bodies.

No action needed. This ingredient is safe at amounts used in supplements.

Top-rated products containing Hydroxypropyl Methylcellulose (Capsule)

These 20 highest-scoring supplements in our database use Hydroxypropyl Methylcellulose (Capsule).

Planetary Herbals KSM-66® Ashwagandha Root Extract, 120 Vegetarian Capsules (300 mg per Capsule)
Planetary Herbals KSM-66® Ashwagandha Root Extract, 120 Vegetarian Capsules (300 mg per Capsule)
Product 100 Brand N/A
Planetary Herbals KSM-66® Ashwagandha Root Extract, 60 Vegetarian Capsules (300 mg per Capsule)
Planetary Herbals KSM-66® Ashwagandha Root Extract, 60 Vegetarian Capsules (300 mg per Capsule)
Product 100 Brand N/A
BioGaia Immune Active, Protectis® Capsules, 60 Capsules
BioGaia Immune Active, Protectis® Capsules, 60 Capsules
Product 100 Brand N/A
Source Naturals Vegan True®, Non-GMO Vitamin D3, 50 mcg (2000 IU), 60 Vegan Capsules
Source Naturals Vegan True®, Non-GMO Vitamin D3, 50 mcg (2000 IU), 60 Vegan Capsules
Product 100 Brand N/A
Source Naturals Vegan True®, Non-GMO Vitamin D-3, 50 mcg (2000 IU), 120 Vegan Capsules
Source Naturals Vegan True®, Non-GMO Vitamin D-3, 50 mcg (2000 IU), 120 Vegan Capsules
Product 100 Brand N/A
Planetary Herbals Lion's Mane, 90 Vegan Capsules (500 mg per Capsule)
Planetary Herbals Lion's Mane, 90 Vegan Capsules (500 mg per Capsule)
Product 100 Brand N/A
Planetary Herbals Lion's Mane, 30 Vegan Capsules (500 mg per Capsule)
Planetary Herbals Lion's Mane, 30 Vegan Capsules (500 mg per Capsule)
Product 100 Brand N/A
Planetary Herbals Lion's Mane, 60 Vegan Capsules (500 mg per Capsule)
Planetary Herbals Lion's Mane, 60 Vegan Capsules (500 mg per Capsule)
Product 100 Brand N/A
Douglas Laboratories Vitamin K2 Menaquinone-7, 60 Vegetarian Capsules
Douglas Laboratories Vitamin K2 Menaquinone-7, 60 Vegetarian Capsules
Product 100 Brand N/A
Douglas Laboratories N-Acetyl-L-Cysteine, 900 mg, 90 Vegetarian Capsules
Douglas Laboratories N-Acetyl-L-Cysteine, 900 mg, 90 Vegetarian Capsules
Product 100 Brand N/A
Source Naturals Phosphatidyl Serine 150™, 150 mg, 60 Capsules
Source Naturals Phosphatidyl Serine 150™, 150 mg, 60 Capsules
Product 100 Brand N/A
Sacred Nutrient Ashwagandha Organic Extra Strength Supplement with Black Pepper for Stress & Mood Support, Energy 300mg Extract (Equivalent 3000mg Herb), 100 Capsules
Sacred Nutrient Ashwagandha Organic Extra Strength Supplement with Black Pepper for Stress & Mood Support, Energy 300mg Extract (Equivalent 3000mg Herb), 100 Capsules
Product 100 Brand N/A
Douglas Laboratories B-Complex with Metafolin L-5-MTHF, 60 Vegetarian Capsules
Douglas Laboratories B-Complex with Metafolin L-5-MTHF, 60 Vegetarian Capsules
Product 95 Brand N/A
Country Farms Super Fruits & Veggies, 2 Pack, 180 Capsules Each
Country Farms Super Fruits & Veggies, 2 Pack, 180 Capsules Each
Product 93 Brand N/A
Country Farms Super Fruits & Veggies, 2 Pack, 180 Capsules Each
Country Farms Super Fruits & Veggies, 2 Pack, 180 Capsules Each
Product 93 Brand N/A
MaryRuth's NADH Capsules, NAD+ Precursor, Trans-Resveratrol, Energy Metabolism, Vegan
MaryRuth's NADH Capsules, NAD+ Precursor, Trans-Resveratrol, Energy Metabolism, Vegan
Product 93 Brand N/A
Source Naturals Ultra-Mag™, 180 Vegan Capsules
Source Naturals Ultra-Mag™, 180 Vegan Capsules
Product 90 Brand N/A
Source Naturals Ultra-Mag™, 360 Vegan Capsules
Source Naturals Ultra-Mag™, 360 Vegan Capsules
Product 90 Brand N/A
Source Naturals Propolis Extract, 500 mg, 60 Capsules
Source Naturals Propolis Extract, 500 mg, 60 Capsules
Product 87 Brand N/A
Source Naturals Coenzyme Q10, 200 mg, 60 Capsules
Source Naturals Coenzyme Q10, 200 mg, 60 Capsules
Product 87 Brand N/A
Related Ingredients
100% Vegetarian Capsule (Cellulose, Water) Safe Beef Gelatin Capsule Safe Bovine Gelatin Safe Capsule (Bovine Gelatin) Generally Safe Capsule (Fish Gelatin) Generally Safe Capsule (Gelatin) Generally Safe Capsule (Hydroxypropyl Methylcellulose) Safe Capsule (Hydroxypropylmethylcellulose) Safe
Frequently Asked Questions
Is Hydroxypropyl Methylcellulose (Capsule) safe in supplements?

Yes. Hydroxypropyl Methylcellulose (Capsule) is rated safe for use in dietary supplements at typical levels. This rating is based on regulatory assessments, published safety research, and its long history of use in the supplement industry. It is widely accepted by major regulatory bodies including the FDA and EFSA. In GoodSupp's database, 20 products contain this ingredient. Consult your healthcare provider if you have specific concerns.

What is Hydroxypropyl Methylcellulose (Capsule) and why is it in my supplement?

A plant-derived polymer used to make vegetarian capsules. It forms the capsule shell that contains and protects the supplement's active ingredients, dissolving in the digestive tract to release the contents. It appears in 20 products in the GoodSupp database.

Is Hydroxypropyl Methylcellulose (Capsule) natural or synthetic?

Hydroxypropyl Methylcellulose (Capsule) is naturally derived, meaning it comes from natural sources such as plants, minerals, or animal products rather than being chemically synthesized. Natural-origin ingredients are preferred by many consumers, though it's important to note that 'natural' does not automatically mean 'safer' — safety depends on the specific substance, its purity, and the amount used. The safety rating assigned by GoodSupp is based on the ingredient's actual safety profile, not its origin.

Check Any Supplement's Ingredients

Scan a barcode with GoodSupp to instantly see safety ratings for every ingredient.

Download on App Store
Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.