Disodium Phosphate

Generally Safe BufferSynthetic

Disodium Phosphate is a synthetic buffer used in dietary supplements. Safety rating: Generally Safe. It is generally considered safe for most people at standard doses. Found in 20 supplements in the GoodSupp database. Disodium phosphate is a sodium salt of phosphoric acid.

20 Products use this
Generally Safe Safety rating
Buffer Category
No Natural origin

Safety Verdict: Generally Safe

High doses may cause electrolyte imbalances.

What is Disodium Phosphate?

Disodium phosphate is a sodium salt of phosphoric acid.

Common Names Disodium Phosphate
Type Buffer
Origin Synthetic / Manufactured
Safety Rating Generally Safe

Why is Disodium Phosphate used in supplements?

It is used as a buffering agent to maintain pH levels.

Role in supplements: Buffer — maintains pH stability to protect active ingredients and reduce stomach irritation.

Should you be concerned about Disodium Phosphate?

Generally no. Disodium Phosphate is considered safe for most people at typical supplement doses. Some individuals may want to be aware of minor sensitivities.

High doses may cause electrolyte imbalances.

Low risk. Generally safe for most people in supplement amounts.

Top-rated products containing Disodium Phosphate

These 20 highest-scoring supplements in our database use Disodium Phosphate.

Gorilla Mind Gorilla Mode Mango Peach
Gorilla Mind Gorilla Mode Mango Peach
Product 93 Brand N/A
Gorilla Mind Mode®, Pre-Workout Formula, Tigers Blood, 1.76 lb (800 g)
Gorilla Mind Mode®, Pre-Workout Formula, Tigers Blood, 1.76 lb (800 g)
Product 91 Brand N/A
Raw Nutrition Burn, Thermogenic Powder, Sweet Citrus, 18.2 oz (516 g)
Raw Nutrition Burn, Thermogenic Powder, Sweet Citrus, 18.2 oz (516 g)
Product 90 Brand N/A
Raw Nutrition Burn, Thermogenic Powder, Peach Rings, 18.2 oz (516 g)
Raw Nutrition Burn, Thermogenic Powder, Peach Rings, 18.2 oz (516 g)
Product 90 Brand N/A
Natural Extract PRE-WORKOUT - TROPICAL SUNRISE
Natural Extract PRE-WORKOUT - TROPICAL SUNRISE
Product 89 Brand N/A
Revive Fiber, Chocolate, 11 oz (312 g)
Revive Fiber, Chocolate, 11 oz (312 g)
Product 87 Brand N/A
Gorilla Mind Gorilla Mode Nitric Mango Peach
Gorilla Mind Gorilla Mode Nitric Mango Peach
Product 86 Brand N/A
Redcon1 Total War Grape
Redcon1 Total War Grape
Product 86 Brand N/A
JYM Supplement Science Pre JYM®, High-Performance Pre-Workout, Pineapple Strawberry, 1.7 lbs (780 g)
JYM Supplement Science Pre JYM®, High-Performance Pre-Workout, Pineapple Strawberry, 1.7 lbs (780 g)
Product 85 Brand N/A
Redcon1 Total War, Preworkout, Sour Gummy Bear, 15.77 oz (447 g)
Redcon1 Total War, Preworkout, Sour Gummy Bear, 15.77 oz (447 g)
Product 85 Brand N/A
Redcon1 Total War, Pre-Workout, Orange Crush, 15.66 oz (444 g)
Redcon1 Total War, Pre-Workout, Orange Crush, 15.66 oz (444 g)
Product 85 Brand N/A
Redcon1 Total War, Pre-Workout, Blue Raspberry, 15.77 oz (447 g)
Redcon1 Total War, Pre-Workout, Blue Raspberry, 15.77 oz (447 g)
Product 85 Brand N/A
Redcon1 Total War, Preworkout, Strawberry Kiwi, 15.56 oz (441 g)
Redcon1 Total War, Preworkout, Strawberry Kiwi, 15.56 oz (441 g)
Product 85 Brand N/A
Redcon1 Total War, Pre-Workout, Blue Lemonade, 15.56 oz (441 g)
Redcon1 Total War, Pre-Workout, Blue Lemonade, 15.56 oz (441 g)
Product 85 Brand N/A
Redcon1 Total War, Pre-Workout, Green Apple, 15.66 oz (444 g)
Redcon1 Total War, Pre-Workout, Green Apple, 15.66 oz (444 g)
Product 85 Brand N/A
Redcon1 Total War, Pre-Workout, Tiger's Blood Cherry & Coconut, 15.66 oz (444 g)
Redcon1 Total War, Pre-Workout, Tiger's Blood Cherry & Coconut, 15.66 oz (444 g)
Product 85 Brand N/A
Redcon1 Total War, Pre-Workout, Rainbow Candy, 15.56 oz (441 g)
Redcon1 Total War, Pre-Workout, Rainbow Candy, 15.56 oz (441 g)
Product 85 Brand N/A
Nutrex Research Outlift® Clinical, Miami Vice, 22.18 oz (628.9 g)
Nutrex Research Outlift® Clinical, Miami Vice, 22.18 oz (628.9 g)
Product 80 Brand N/A
Nutrex Research Outlift® Clinical, Fruit Punch, 22.46 oz (636.61 g)
Nutrex Research Outlift® Clinical, Fruit Punch, 22.46 oz (636.61 g)
Product 80 Brand N/A
Nutrex Research Outlift® Clinical, Blueberry Lemonade, 22.57 oz (639.91 g)
Nutrex Research Outlift® Clinical, Blueberry Lemonade, 22.57 oz (639.91 g)
Product 80 Brand N/A
Related Ingredients
Frequently Asked Questions
Is Disodium Phosphate safe in supplements?

Disodium Phosphate is rated generally safe for most people at amounts commonly found in supplements. While the overall safety profile is favorable, some individuals may experience minor sensitivities. High doses may cause electrolyte imbalances. In GoodSupp's database, 20 products contain this ingredient. Consult your healthcare provider if you have specific concerns.

What is Disodium Phosphate and why is it in my supplement?

Disodium phosphate is a sodium salt of phosphoric acid. It appears in 20 products in the GoodSupp database.

Is Disodium Phosphate natural or synthetic?

Disodium Phosphate is synthetically produced, meaning it is manufactured through chemical processes rather than directly extracted from natural sources. Synthetic ingredients are extremely common in supplements and are not inherently less safe than natural alternatives. In many cases, synthetic production allows for higher purity and more consistent quality. The FDA regulates both natural and synthetic supplement ingredients under the same safety standards. GoodSupp rates ingredients based on their actual safety data regardless of whether they're natural or synthetic.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.