Capsule (Hypromellose)

Safe CapsuleNatural

Capsule (Hypromellose) is a naturally derived capsule used in dietary supplements. Safety rating: Safe. It is widely considered safe at typical supplement doses. Found in 20 supplements in the GoodSupp database. Hypromellose, also known as HPMC, is a plant-derived polymer used to make capsules.

20 Products use this
Safe Safety rating
Capsule Category
Yes Natural origin

Safety Verdict: Safe

This ingredient is rated safe for use in dietary supplements.

What is Capsule (Hypromellose)?

Hypromellose, also known as HPMC, is a plant-derived polymer used to make capsules.

Common Names Capsule (Hypromellose), HPMC Capsule, Vegetarian Capsule
Type Capsule
Origin Natural / Plant-derived
Safety Rating Safe

Why is Capsule (Hypromellose) used in supplements?

It is used to encapsulate the supplement ingredients.

Role in supplements: Capsule material — forms the shell that contains the supplement's active ingredients. Dissolves in the stomach to release contents.

Should you be concerned about Capsule (Hypromellose)?

No. Capsule (Hypromellose) is widely regarded as safe for use in dietary supplements at typical levels. It has a long history of use and is accepted by major regulatory bodies.

No action needed. This ingredient is safe at amounts used in supplements.

Top-rated products containing Capsule (Hypromellose)

These 20 highest-scoring supplements in our database use Capsule (Hypromellose).

XYMOGEN OptiMag 125, 240 Vegetarian Capsules
XYMOGEN OptiMag 125, 240 Vegetarian Capsules
Product 100 Brand N/A
XYMOGEN OptiMag 125, 120 Vegetarian Capsules
XYMOGEN OptiMag 125, 120 Vegetarian Capsules
Product 100 Brand N/A
Metagenics Ceralin®, 90 Capsules
Metagenics Ceralin®, 90 Capsules
Product 96 Brand N/A
NEURIVA Memory 3D
NEURIVA Memory 3D
Product 90 Brand N/A
ALPHA LION SuperHuman Test, 90 Capsules
ALPHA LION SuperHuman Test, 90 Capsules
Product 89 Brand N/A
Bariatric Advantage Ultra Multivitamin Iron-Free High Potency
Bariatric Advantage Ultra Multivitamin Iron-Free High Potency
Product 89 Brand N/A
Advanced Orthomolecular Research AOR Chanca Piedra, 500 mg, 90 Capsules
Advanced Orthomolecular Research AOR Chanca Piedra, 500 mg, 90 Capsules
Product 87 Brand N/A
Advanced Orthomolecular Research AOR Opti-Cholest, 60 Capsules (500 mg per Capsule)
Advanced Orthomolecular Research AOR Opti-Cholest, 60 Capsules (500 mg per Capsule)
Product 87 Brand N/A
Advanced Orthomolecular Research BenaGene Advanced Cellular Health, 30 Capsules
Advanced Orthomolecular Research BenaGene Advanced Cellular Health, 30 Capsules
Product 87 Brand N/A
Divine Health® Silical® 1 Bone Health - 120 Capsules (30 Servings)
Divine Health® Silical® 1 Bone Health - 120 Capsules (30 Servings)
Product 87 Brand N/A
Neuriva Memory Dietary Supplement Capsules - 1 Dose
Neuriva Memory Dietary Supplement Capsules - 1 Dose
Product 85 Brand N/A
Advanced Orthomolecular Research AOR R-Lipoic Acid, 150 mg, 90 Capsules
Advanced Orthomolecular Research AOR R-Lipoic Acid, 150 mg, 90 Capsules
Product 83 Brand N/A
Metagenics UltraFlora® Immune Booster Probiotic, 30 Capsules
Metagenics UltraFlora® Immune Booster Probiotic, 30 Capsules
Product 83 Brand N/A
Nature's Nutrition Probiotics for Women 50 Billion CFU - 16 Strains
Nature's Nutrition Probiotics for Women 50 Billion CFU - 16 Strains
Product 83 Brand N/A
Natrol Sleep & Restore, 60 Capsules
Natrol Sleep & Restore, 60 Capsules
Product 80 Brand N/A
Natrol Sleep & Restore, Melatonin Free, 60 Capsules
Natrol Sleep & Restore, Melatonin Free, 60 Capsules
Product 78 Brand N/A
XYMOGEN MemorAll, 60 Vegetarian Capsules
XYMOGEN MemorAll, 60 Vegetarian Capsules
Product 77 Brand N/A
Advanced Orthomolecular Research AOR Estro Freedom, 60 Capsules
Advanced Orthomolecular Research AOR Estro Freedom, 60 Capsules
Product 75 Brand N/A
Double Wood Supplements LJ100 Tongkat Ali, 100 mg, 120 Capsules
Double Wood Supplements LJ100 Tongkat Ali, 100 mg, 120 Capsules
Product 75 Brand N/A
Advanced Orthomolecular Research AOR Multi Basics 3, 180 Capsules
Advanced Orthomolecular Research AOR Multi Basics 3, 180 Capsules
Product 74 Brand N/A
Related Ingredients
Frequently Asked Questions
Is Capsule (Hypromellose) safe in supplements?

Yes. Capsule (Hypromellose) is rated safe for use in dietary supplements at typical levels. This rating is based on regulatory assessments, published safety research, and its long history of use in the supplement industry. It is widely accepted by major regulatory bodies including the FDA and EFSA. In GoodSupp's database, 20 products contain this ingredient. Consult your healthcare provider if you have specific concerns.

What is Capsule (Hypromellose) and why is it in my supplement?

Hypromellose, also known as HPMC, is a plant-derived polymer used to make capsules. It forms the capsule shell that contains and protects the supplement's active ingredients, dissolving in the digestive tract to release the contents. It appears in 20 products in the GoodSupp database.

Is Capsule (Hypromellose) natural or synthetic?

Capsule (Hypromellose) is naturally derived, meaning it comes from natural sources such as plants, minerals, or animal products rather than being chemically synthesized. Natural-origin ingredients are preferred by many consumers, though it's important to note that 'natural' does not automatically mean 'safer' — safety depends on the specific substance, its purity, and the amount used. The safety rating assigned by GoodSupp is based on the ingredient's actual safety profile, not its origin.

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Disclaimer: GoodSupp provides independent supplement quality analysis for informational purposes only. Scores are generated algorithmically based on ingredient profiles, brand certifications, and public records. This is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Product data is sourced from manufacturer labels and public databases. GoodSupp is not affiliated with any supplement brand.